The following is literally my history as a researcher, reproduced as a CV for this page.  I pulled it from my pages at ResearchGate.org, a social website where academicians store and share their professional history.  The text alone for that page was 69 pages in length, +/- 1 page (so spare the old growth forest and don’t try printing this stuff out).  [NOTE: A Research Gate – Projects List has also been posted, much simpler to scan through.)

The purpose of posting this page has mostly to do with the eclectic nature of my background.  My research history and my productivity over the past three decades have been quite varied, due to the time I had to search for new research topics over the decades.  

When I first began producing this blog site around 2005, it was just to serve as my resume, mostly for job-seeking purposes.  

Since I was then working with the Medicaid/Medicare program, overseeing a fairly large federally series of population health studies, I lacked the need for the use of this site much as a CV/Resume site.  So,  a few months later I converted brianaltonenmph.com to my personal blog site.  

Next I realized it was the perfect place to post all of my work I had accrued over the years on floppies.  And so I began my postingmy work, beginning with my earliest accomplishments such as my ten years of research of Dr. Cornelius Osborn, Revolutionary War Physician, and Colonial New York Lt.-Governor Cadwallader Colden.  Next came my Oregon trail work, followed by any other  research I had stored on the old 3.5 in floppies that had to be pulled and made use of (I haven’t worked on the zip drives yet).  These floppies also included the research I did on the first use of American plants as medicines, and thus all of my pages on the writings of the original explorers, the missions, the trappers, Hudson Bay’s Company work, Oregon Trail pioneers, and so on and so forth, another several thousand pages worth of data pulled from my disks over one or two winters.   

At times the content of these projects does appear a bit self-centered.  But the reasons for some of the expressions in my work are two-fold.  First, this work represents how I taught many of my course topics at PSU–none of my students never knew what side I took on any of my teachings over the 20 years (i.e. was I for herbal medicine or against it?  Did I believe these things actually work or not? etc.).  Second, the goal was to use these postings to counter the statements and criticisms I received over the years for “not jumping through hoops” with my research, although I regular reported this work at the Oregon Academy of Sciences quite often, was published a few times, and recognized by the public and certain government offices for my expertise.  As a university researcher, lecturer and expert in several fields, I especially got resistance from professors in other departments; I was from the department of chemistry and taught history, anthropology, etc. (See my Rights of the Shaman page for an example of this problem.)    

Therefore, for various reasons, this page is essentially a fairly lengthy autobiography of my scholarly work, with a little bit of my personal life intertwined with my writings every now and then if you go to the actual research that is posted (i.e. see my Health in the Pacific Northwest essay).

**********************************************************************

Brian Altonen 
MPH (Spatial Epidemiology), MS (Medical Geography/Environmental Science).   
PSU, Portland OR 97207

Skills (87)

  • Successful
  • Innovative
  • SAS
  • Spatial Analyses and GIS/RS.
  • NPO grant/funding/research assistance.
  • GIS fieldwork/analyst. New applications for ESRI GIS
  • Taxonomy
  • phytochemistry and ethnobotanical information in relation to uses
  • adulteration or ingredients substitution.
  • Thin layer chromatography (TLC)
  • Biostatistical Methods
  • symmetry
  • Caremark
  • ArcInfo
  • ArcView GIS and extensions
  • ArcGIS
  • Idrisi32 and derivatives
  • ERDAS RS tools
  • MrSID
  • GeoTIFF
  • dlgv32
  • MultiSpecW32
  • Crystal Reports
  • Advanced Excel/Access
  • Analyse-It
  • Paradox
  • panorama
  • ClusterSeer
  • SaTScan
  • Quattro Pro
  • S-Plus
  • SPSS
  • vb
  • Ethnograph
  • Atlas/ti
  • NUDIST
  • SAS Base
  • Statistical Software
  • Research Data
  • Creative analyst and proprietary formula writer for large companies
  • Successful analyst and decoder of “corporate black box formulas”
  • Successful grantwriter (letter and form grants).
  • Producer of algorithms used to enhance detectability of specific objects.
  • Producer of algorithms used to summarize and index all statistical outcomes, using multiple forms of comparison modules in a single step.
  • Producer of time-saving, automated analytic tools for institutional periodic record-update
  • Developer and producer of teaching materials and products for field ethnobotany, GIS, epidemiology, historical geography
  • Inventor of text analysis tool for use in survey and interview/focus groups
  • Inventor of algorithms used to evaluate GIS and Population patterns for SIGs
  • developer of ecoanalytic tools used for GIS/phytoecology research
  • NPOs leader/group leader
  • Natural historan for parks/recreation related sigs.
  • Producer of an artificial surface DEM-derived modelling equation, applied to Remote Sensing/GIS outcomes in order to map results and develop prediction model for waterside/shoreline disease patterns
  • Population health specialist for extremely large datasets (1M-300M).
  • Successful data miner/analyst responsible for developing/inventing new uses.
  • Developer of innovative formulas (A B) and methods used to evaluate cost in relation to health
  • Developer of Gaussian LogCost statistical analysis technique for the same.
  • Developer of sql tool for describing and analyzing large and small regions.
    • 150-175 companies/clients
    • 30+ SIC groups
    • 50 states
    • 15 N. Amer. regions
    • agencies and npos ($10M-$50M+ annual income).
  • Analyst for large and small or special population HEDIS/NCQA health-research
  • Parametric and Nonparametric analyst for teacher-students activities, pre-post analyses and long term follow-up studies using grounded theory methodology and open survey response patterns evaluated as follows:
    • for clinical practice behaviors in relation to educational content and long term memory-related outcomes.
    • use of a semiautomated Qualitative analysis tools for text-analyses of EMR related or hand scribed pre-post-clinical based patient care survey results.
  • Discovered/invented facial recognition formulas; developed and tested numerous other applications of these formulas for statistical significance measurements focused on spatial analyses and land/spatial content (population/count density) or surface changes (i.e. surface, slope, shape, transect, linear and curvature or landform comparisons).
  • Developed innovative GIS Spatial Epidemiology/Disease Ecology methodology.
  • Developed an automated advanced population health measurement tool.
  • Developed automated assessment tools for hierarchical datasets.
  • Developed automated populations/demographics quarterly census reporting.
  • Designed a tool used to monitor nurse hotline calls/database-derived info
  • Designed a tool used to automatically monitor
  • Managed and Produce alerts for exceptionally large prescription databases with signs or evidence of Fraud and Quackery, Misuse/Abuse, etc.

Fields of Specialty

  

AWARDS

STAR, Denver Health. see end page lists in http://www.chlpi.org/wp-content/uploads/2014/01/PATHS-Innovations-and-Insights-in-Medicaid-Managed-Care-3.21.16.pdf

ESRI. see http://www.directionsmag.com/pressreleases/gis-users-excel-in-communication-service-and-vision-for-health-and-human-se/110759

GIS Users Excel in Communication, Service, and Vision for Health and Human Services Applications

ESRI Honors Award-Winning Health GIS Programs and Projects

Redlands, CaliforniaESRI is pleased to announce the winners of the 2006 Communication, Service, and Vision Awards given to users of geographic information system (GIS) technology in the health and human services fields. Denver Health Managed Care (Denver, Colorado), the World Health Organization (WHO) ( Geneva, Switzerland), and the National Cancer Institute (NCI) (Bethesda, Maryland) received the awards during ESRI’s annual Health GIS Conference held at the Colorado Convention Center in Denver, Colorado, in October.

Accepting the 2006 Communication Award was Brian Altonen, quality analyst for Denver Health Managed Care. This award is given to an organization participating in the conference’s Map Gallery for the poster that best communicates concepts, illustrates methods, creatively integrates data, and is relevant to health and human services. Altonen’s award-winning poster, titled Applications of GIS to West Nile Virus Surveillance Programs: A Study of Disease Ecology, illustrated how geospatial analysis of mosquito trap results, dead bird sightings, and wetlands is used to pinpoint infected mosquito breeding areas.

~~~ . . .

 

TEACHING

Biostatistics, Advanced Nonparametric Techniques, Survey Design and Methodology, Qualitative/Quantitative Research Methods GIS (beginners and intermediate/advanced), Medical Geography/Disease Ecology Remote Sensing/AVHRR Natural Products, Metabolism/Phytochemistry/chemotaxonomy, The Evolution of Plants and Plant Compounds, Ethnobotany Field Botany, History of medicine, History of pharmacology, Bioengineered Plant Products.

CITED WORK

36th Annual Meeting of the Society for Medical Decision Making

Abstracts

PS3-43 An Evaluation of Cardiac Procedures after Use of a Wearable Cardioverter-Defibrillator

Health Services and Policy Research (HSP)

Mark Tankersley, BSPharm, PhD, HealthHelp, Houston, TX, Anthony DeFrance, MD, HealthHelp, Stanford University, San Anselmo, CA, Brian Altonen, MS, MPH, HealthHelp, Beacon, NY and James Long, BSBA, Humana, Louisville, KY

Purpose: The implantable cardioverter-defibrillator (ICD) has been shown to improve survival from sudden cardiac arrest and to improve overall survival in several populations at high risk for sudden cardiac death. However, there remain situations in which implantation of an ICD may be inappropriate or delayed, and a wearable cardioverter-defibrillator (WCD) may be an acceptable alternative approach for the prevention of sudden cardiac death. The purpose of this analysis was to describe use of WCD and subsequent cardiac procedures in clinical practice.

Methods: Patients who used a WCD were identified using retrospective claims from the Humana Database (January 2011–April 2013). Patients were followed for the duration of WCD use, and use of an ICD within 60 days of WCD discontinuation was reported. Cardiac diagnostic and interventional procedures during the 240 days post-WCD were also reported.

Results: Use of WCDs was low in this population but increased twofold year over year during the evaluation period. A total of 1,199 patients used WCDs between 2011 and 2013 with a mean duration of use of 2.4 months (95% confidence interval 2.33–2.5). The top diagnoses for which the WCDs were prescribed included non-ischemic primary cardiomyopathies, acute myocardial infarction (MI), and old MI, collectively representing 78% of the total. Sixty-two percent (n=746) of WCD users did not get an ICD within 60 days. Forty-seven percent (n=567) of WCD users did not have any additional targeted cardiac procedures. Of those who did have a procedure (53%, n=632), cardiac nuclear medicine and cardiac catheterization represented the majority of all post-WCD diagnostic procedures (44%), and ICDs made up the largest group of interventional procedures (27%).

Conclusion: WCD is intended as a temporary solution with the main indications being a bridge to ICD implantation or until the arrhythmic substrate subsides. In this analysis, we found that the majority of WCD users did not got on to have an ICD, and nearly half had no additional targeted cardiac procedure. These data from clinical practice may help to determine the role of WCD in cardiac therapy.

 

Source:
An Evaluation of Cardiac Procedures after Use of a Wearable Cardioverter-Defibrillator. Med Decis Making January 2015 vol. 35 no. 1 E1-E167, PS3-43.  doi: 10.1177/0272989X14559740

http://mdm.sagepub.com/content/35/1/E1.full

PROJECTS

Feb 2013–present 

Research: Hybrid Grid-Point Mapping Overlays Algorithm

USA · Beacon, NY

Developed algorithm to overlay accurate grid mapping data with point specific base map data, producing a more accurate 3D isoline projection of US case counts, prevalence, risk, cost, etc., based upon their relation to small area grid cell features.

Jan 2013–present

  

Research: Cultural Medicine Surveillance

USA · Colorado

Cultural epidemiology was added to a standard population health monitoring program. Hispanic population evaluated for >300 cultural bound, cultural-linked, culturally prevalent chronic disease, or imported infectious/non-infectious ICDs.

Nov 2012–present

Research: Transcribing Wartime Medical Documents

NHPRC, War Department Papers

USA · Newport, RI

Transcribing military medical documents for the 1790 to 1800/1805 yellow fever epidemic period, evaluating disease migration routes and public and government reactions to these epidemics (quarantine protocols established). A Federally sponsored Project.

Nov 2012–Jan 2013

Research: GridEconomy Metrics tool developed

Programming the applications for my National Population Grid methodology tools. Automated and semi-automated report generating processes are being developed to report on Demog., Risk, Prediction, Cost-Consumer analyses, utilization, etc.

Oct 2012–Nov 2012

Research: The James River Epidemic of 1800

Utilized research methods developed for disease mapping and analysis in GIS to identify the species, source and spatial history of the 1766-1806 James Fever Ringworm epidemic first documented by Th. Jefferson.

Aug 2012–present  

Research: Public Health and African/African American Slavery in the U.S.

Research of 1790-1860 medical writings and the major contributions of African culture to US medical history, esp. for ethnobotany, culturally-bound syndromes and practices (infibulation mapping), and culturally-linked disease patterns.

Aug 2012–Sep 2012  

Research: Plantae Coldenghamiae Translation (Latin to English)

USA · Beacon, NY

Translating Cadwallader Colden’s 1749,1751 Linnaean Publication Plantae Coldenghamiae (Plants of Coldengham, New York)

May 2012–present  

Research: National population health grid map Videos

Undisclosed

Applied innovative algorithms to mapping nation’s stats at 20 mile grid level for 450 culturally or socially significant icds, v-codes and e-codes., by gender/1-year age groups, producing 1000+ analyses. Some map videos posted at blog, YouTube.

May 2012–Nov 2012

  

Research: “An Extraordinary Disease” in Nantucket in 1763

Utilized research tools and methodology developed in GIS for analyzing and identifying the December 1763 Nantucket epidemic typically considered yellow fever. Spatio-temporal behaviors and local climate and demographic history suggest it to be Typhoid.

Apr 2012–present  

Research: Foreign Disease Penetration

Applied grid analysis to researching in-migration or penetration of borders by rare foreign born diseases. Approximately 150 highly fatal zoonotic diseases evaluated. Produced digital videos of results, some of which may be posted.

Apr 2012–present  

Research: Unique Signs of Child Abuse

Aside from Abuse ICDs, Other ICDs, Ecodes and Vcodes were evaluated to define high risk regions on a grid cell map. Indicators included poor nutrition diagnosis, birth with a drug addiction, failure to immunize, shaken baby and battered child events.

Apr 2012–present  

Research: Terrorism and bioterrorism in the US.

Self-explanatory. New grid mapping and 3D rotating imagery methods employed. Amazing results. After these are posted, Password is required for entry.

Mar 2012–Jun 2012  

Research: Epidemiological Data 3D-Imagery in SAS

Developed a program for producing a 360 degrees rotating map presentation of 3D Grid maps of the US with epidemiological data presented along the z-axis. A rotating image process was developed to display results from all angles on a slightly slanted x-y plane of the United States. This process makes for an excellent powerpoint illustration of outcomes, displaying national health statistics (macros, etc.). Applicable and most effective for displaying 3d (cuboid), false cuboid, isoline, and surfaceplot models. Prototype readied for presentation at..

Mar 2012–Aug 2012  

Research: Mapping ICDs using the new US Population Health Grid Methodology

Applications for a new SAS False Cuboid (bivariate 3D histogram) Technique used to map national disease (ICD) stats under development. Techniques developed for presenting overall N and population density relative to ICD9 n and prevalences, with raw scores and coarsely to finely adjusted scores mapped. Undisclosable other population risk data to be tested as well. An additional stepwise process is under development for age-gender adjustments. Several major polygon-centroid approaches have been tested for the assignment of locations of data. For prototype of US grid maps, the grid used to cover the US measures 2750 mi max E-W (width) x 2575 mi N-S max; this rectangle produced a grid with cells of approx. 25 mi x 25 mi (lat-change related fine tunings are still in process). ICDs to be testing include those for diseases/conditions with known regional (SW US age-defined post-retirement age ICDs, Great Lakes area child-mother ICD associations determine using previous mapping techniques), or lat-long relationships (i.e. Cold-induced hemagglutination syndromes, heat exhaustion, MS), and conditions with cultural relations defined physiologically (ICD9 based African cardiomyopathy 425.2, Takotsubo 429.83 ), socioculturally and SES-related (V15.81 non-compliance), or culturally-bound syndromes (i.e. ICD9 729.2* infibulation, SUNDS). Population N = 30M to 135M.

Jan 2012–Aug 2012  

Research: A SAS-based Disease Mapping Technique

The 3D grid modeling formula developed for use of SAS to correlate the results for three measures per patient can be applied to the development of a simple grid-like layout of cases and their metrics. This serves as a substitute for SAS/GIS when SAS/GIS is not available. Since it produces maps fairly quickly, the lack of GIS related programming serves more as a benefit than a hindrance. The disadvantages to this technique is that it is not as easily used to produce anything beyond the simple 3D mapping process, such as a map used for developing intervention programs based on lat-long features or defining methods for interventions based on locations of facilities. The model this method produces serves simply as a 3D grid or surface projection of the results produced. Incidence and prevalence are usually the best mapped spatial epidemiological features using this methodology, although population and sociological features like population percentages and average age or family size may be mapped as well. The primary requirement for this method is having some form of lat-long measures to implement this process. These are used to define the base grid (2 of the 3 axes) on the 3D formulas employed in SAS. The z-axis in turn is treated much like elevation and the plane produce is evaluated the same as a land surface feature. ICD or disease mapping can be handled in this fashion by first producing the data for individual diseases and any metrics related to those diseases, followed by the development of a means to cluster or grid map this data. The SAS formulas developed naturally produce these grids; the only decisions made by programmers pertains to grid cell size and how these are measured. The SAS formula then defines locations for each ofthe patients, which naturally are placed upon the grid cell centroid. Cobbled (barred), contour and surface versions can then be p[riduced using this methodology, in order to uncover peaks of incidence/prevalence. Age-gender adjustments may also be made for each cell as a part of this process. Two techniques and two formulas were developed to produce these 3D outcomes.

Dec 2011–Feb 2012  

Research: National Age-Gender Suicide Study

Developed methodology for modeling Suicides, based on 10 year dataset, with Suicides categorized using ICDs in combination with Vcodes. Numerous significant Age-Gender behavioral differences were noted. [Final report stll needs to be generated.]

Dec 2011–Dec 2011  

Research: National Age-Gender Acute/Chronic Diseases Study

We typically consider acute diseases to be significantly different from chronic diseases. Acute diseases are at times considered a precursor to the more severe chronic disease state of similar clinical appearance. Age-gender analysis should demonstrate specific differences between acute and chronic disease distributions. A number of disease types were evaluated for this relationship. Some diseases like acute versus chronic pancreatitis demonstrate absolutely no statistically significant differences in age-gender distributions. Diseases with ICD codes defined in order to define states did demonstrate staging, such as the various levels of chronic renal, liver, heart and lung diseases. Acute versus chronic did not demonstrate these notable differences suggesting a difference in severity between the two. The possibility that acute and chronic diseases of the same organ state lack these differences suggests that age is a primary determinant of risk and severity, regardless of the cause for acute versus chronnic disease onsets. Causes are multiple, but tend to effect the human body around the same stage in life.

Nov 2011–Feb 2012  

Research: National Age-Gender Progressive Degenerative Genetic Diseases Study

ICD9 defined cases were evaluated for all genetic diseases with known early morbidity and mortality. Age-gender asymmetries were noted in various forms. Controversial findings. Go to https://brianaltonenmph.com/gis/population-health-profiles/part-iii-population-health-application/special-topics/degenerative-lifelong-and-degenerative-fatal-diseases/, type “Asklepius”

Nov 2011–Jan 2012  

Research: National Age-Gender E-codes and MVAs Study

Standard Population Health Research Method utilized via SAS/SQL. Evaluations based on ICDs and E codes. Specific Age-Gender differences noted that were specific to vehicle type and history. Passenger-Driver and vehicular profiles, accident types and degree of care required demonstrate high amount of gender specificity.

Nov 2011–Apr 2012  

Research: 3D modeling of population health statistics: Cost Analysis

Developed 3D modeling formulas and methods in SAS and SQL for population health based predictive modeling of populations with specific age-gender profiles. Cuboidal, false cube, and surfaceplot techniques developed. Applied to cost-patient copay data as potential deterrent to health care. A unique relationship between cost and prevalence-incidence [PI] exists. Mortality reduces numbers of patients following peak age for PI of about 52-57. Surviving patients begin to accrue costs for continued health. These costs increase exponentially and maximize at an age between 65 and 85 years of age for most companies and insurers. Cost and # cases are inversely proportional and demonstrate a fairly predictable stable relationship to which costs and risk can be assigned based on ICD type, age and gender. Location plays a small role in defining these outcomes when regions tested are large (multistate). Much smaller regions may demonstrate socioeconomically based differences in cost for long term care, as well as likelihood for survival into these older, high cost years.

Nov 2011–Dec 2011  

Research: National Age-Gender Population Health Study, By Regions with Potential Physiographic Influence

15-24 regions of the US were identified based on a review of Census Bureau, NCQA and other Federal standards. Regions were evaluated and compared with the rest of the country for statistically significant Incidence/Prevalence differences. Temperature, climate, humidity, latitude, topography, and local land use type are expected to influence each of these disorders in some ways. Large regions were defined reducing likelihood for topographic influences, but regions defined by unique features such as lat, proximity to ocean, neotropical settings, were evaluated for specific diseases possibly linked to these settings. The following potentially regional diagnoses were evaluated: Cold-induced hemagglutination, lyme disease, stroke, heat exposure, exhaustion, and stroke, Raynaud’s Syndrome, asthma, UR disorders.

Nov 2011–Apr 2012  

Research: 3D modeling of SIC population statistics

Developed 3D modeling formulas and methods in SAS and SQL for >100 companies, >6.5M patients, reclassifying them into Standard Industrial Classification derived groups. These groups were used to define types of population health risks expected due to very unique age-gender distributions that exist between different SIC groups. This in turn may be used for predictive modeling of population based on SIC class and specific age-gender profiles. (SIC methodology derived from Chemical Release Sites studies for the state of Oregon, ca. 1997-2006, in which SIC reclass was used to categorize chemical profiles of site chemical releases, see https://brianaltonenmph.com/3-gis-environmental-health/confirmed-release-inventory-cri-sites/a-sic-based-sites-classification-process/.) Cuboidal, false cube, and surfaceplot techniques developed.

Nov 2011–Feb 2012  

Research: National Age-Gender Gastrointestinal Cancer Study

ICD9 defined cases were evaluated for all GI cancers (malignant and non-malignant) ranging from oral-esophageal to colorectal, for both acute and chronic disease states. Age-gender distributions were evaluated in search of age range and gender related asymmetries. See https://brianaltonenmph.com/gis/population-health-profiles/part-iii-population-health-application/special-topics/

Nov 2011–Jan 2012  

Research: National Age-Gender Traumatic Amputations and Recovery Study

Standard Population Health Research Method utilized via SAS/SQL. Evaluations based on ICDs and ER codes. Specific Age-Gender differences noted to be very specific to amputation type and history, and engagement in related special services including engagement in wheelchair and artificial appendage related services. For partial coverage see https://brianaltonenmph.com/gis/population-health-profiles/part-iii-population-health-application/special-topics/

Nov 2011–Jan 2012  

Research: National Age-Gender Developmental Disease/Disorder Study

Standard Population Health Research Method utilized via SAS/SQL. Evaluations based on ICDs. Specific Age-Gender differences noted to be repetitive between nearly all ICDS regarding gender differences. Male patients display two diagnosis peaks several years apart for the late tee age/early 20s, whereas the diagnoses of females display as a single age peak.

Nov 2011–Feb 2012  

Research: National Age-Gender Liver Disease Study

ICD9 defined cases were evaluated for all Liver Diseases including both acute and chronic disease states. Age-gender distributions were evaluated in search of age range and gender related asymmetries. Chronic degenerative Liver Diseases displayed expected age-variations, with age peak in 50s and evidence for early mortality and a sharp death peak for the more severe cases. This was more pronounced for male versus females.

Nov 2011–Dec 2011  

Research: Regional Age-Gender Study of Non-Compliance Diagnoses

Standard Population Health Research Methods that I developed were utilized via SAS/SQL. Evaluations based on V code for non-compliance (V18.81). Significant Gender differences not noted. Significant age related regional differences noted for: Great Lakes area (17-40 yo < national, 55-70 yo > national), New England (<13 yo and 35-40 yo > national).

Nov 2011–Feb 2012  

Research: National Age-Gender Traumatic Injuries Study Injuries Study

Standard Population Health Research Method utilized via SAS/SQL. Evaluations based on ICDs and ER codes. Age-Gender differences were specific to injury type and part of the body afflicted.

Nov 2011–Feb 2012  

Research: National Age-Gender Fractures, Dislocations and Bone-Joint Injury Study

Standard Population Health Research Method utilized via SAS/SQL. Evaluations based on ICDs and ER codes. Specific Age-Gender differences noted to be very specific to age and gender, enabling the highest risk groups to be defined.

Nov 2011–Apr 2012  

Research: 3D modeling of population health statistics

Developed 3D modeling formulas and methods in SAS and SQL for population health based predictive modeling of populations with specific age-gender profiles. Cuboidal, false cube, and surfaceplot techniques developed. Applied to cost-patient copay data as potential deterrent to health care.

Oct 2011–Dec 2011  

Research: National Age-Gender Abuse and Neglect Study

Utilized new SAS/SQLs to define age-gender distributions for all ICDs related to Child and Adult Abuse and Neglect entries made into the medical records. Very specific distributions exist for sexual abuse, with F>M, and adult sexual abuse >> child abuse. Nutrition neglect demonstrate several age peak and spanned the entire age range. Emotional and psychological abuse demonstrated a much higher frequency in females versus males. Shaken baby syndrome has an early peak age and onset than Battered Child. See https://brianaltonenmph.com/gis/population-health-profiles/part-iii-population-health-application/special-topics/abuse-and-neglect/.

Oct 2011–Dec 2011  

Research: National Age-Gender Psychiatric Syndromes and Behavioral Health Study

Utilized new SAS/SQLs to define age-gender distributions for all Psychiatric ICDs and Behavioral Health conditions. More than 250 ICDs or ICD groups evaluated. Specific age-gender groups demonstrate very unique and predictable age-gender distributions with group differences clearly represented. Numerous age-gender favoring and age-gender specific ICDs could be identified.

Sep 2011–Sep 2011  

Research: National Age-Gender Heart Valve ICDs Study

New statistical method tested for evaluating ICD-related differences across different Age-Gender 1-year Age groups. Three of the four heart values demonstrate no gender asymmetry and similar age range distributions. The fourth heart valve (Pulmonary) demonstrated a larger peak in newborn popualtions.

Sep 2011–Nov 2011  

Research: National Age-Gender Organ Transplants Study

12 types of organ transplants were evaluated for national age-gender distribution, identified using V42 codes. Each organ transplant had a very unique age-gender relationship. See figure depicting these results at https://brianaltonenmph.com/gis/population-health-profiles/part-iii-population-health-application/special-topics/

Sep 2011–Sep 2011  

Research: National Age-Gender Heart Valve ICDs Study

New statistical method tested for evaluating ICD-related differences across different Age-Gender 1-year Age groups. Three of the four heart values demonstrate no gender asymmetry and similar age range distributions. The fourth heart valve (Pulmonary) demonstrated a larger peak in newborn populations.

Sep 2011–Oct 2011  

Research: National Age-Gender Headaches and Migraines Study

The various types of headaches were evaluated for national age-gender distribution, identified using ICD codes. Types of headaches evaluated focused on regular headaches, migraines and cluster headaches. Migraines demonstrates a 5:1 to 6:1 gender specificity with F>>M across all age groups. Cluster headaches demonstrated more age-gender symmetry in its distributions.

Sep 2011–Sep 2011  

Research: National Age-Gender Joint Replacements Study

New statistical method tested for evaluating ICD-related differences across different Age-Gender 1-year Age groups. Vcodes used to define patient population. Peak ages for the various forms of joint replacement were identified. regional age differences were noted along with joint-age-gender relationships.

Aug 2011–May 2012  

Research: National Population Health Age-Gender Studies related to Socioeconomically-linked disease and unhealthy health behavior patterns: Smoking, Drinking and Drug Abuse

Evaluated ICDs codes that detail level and type of abuse and addiction involving alcohol, tobacco products and street drugs. Incidence/Prevalence measured at the age-gender population level. Specific abuse/addiction behaviors demonstrated very unique age-gender differences. For now, see https://brianaltonenmph.com/gis/population-health-profiles/part-iii-population-health-application/special-topics/

Aug 2011–May 2012  

Research: National Population Health Age-Gender Studies related to Socioeconomically-linked disease and unhealthy health behavior patterns: Epilepsy

Evaluated ICDs codes that detail level and type of epilepsy or seizure related syndrome. A nosology or taxonomy of this complex set of ICDs was developed. See https://brianaltonenmph.com/gis/population-health-profiles/part-iii-population-health-application/special-topics/epilepsy/

Aug 2011–Sep 2011  

Research: Regional ICD-based Incidence/Prevalence Disease Research of the US: Modeling Cost Relationships

15-24 regions of the US were identified using methods defined elsewhere. Several methods for evalauting and modeling cost relationships were tested.

Aug 2011–Dec 2011  

Research: National Age-Gender Psychosomatic Syndromes and Health Prevention/Health Promotion Study

Utilized new SAS/SQLs to define age-gender distributions for a number of ICDs and Behavior related Health conditions with significant quality of life impacts on adults of the older working class age (45-54 and 55-64). These ICDs demonstrated very gender specific prevalence distributions, some with F onset 10 years after male peak age onset, a few with the opposite age effect. Male peaks were almost always in their 20s, female peaks almost always in their mid-40s. ICDs evaluation included Diabetes, Lower Back Pain, GERD, Chronic Fatigue Syndrome, Fibromyalgia, Crohn’s Disease, etc. Results suggests there is a universal age-gender relationship involved stress and personal disease management resulting in identical morbidity-mortality effects regardless of disease type for these specific types of diseases or disorders.

Aug 2011–Dec 2011  

Research: The frequency and prevalence behaviors of a controversial African-american cultural practice: infibulation and other female genital surgical practices

Evaluated an exceptionally large US health database for a very rare medical condition ICD-9 entry. Genital manipulation practices involving male and female individuals was assessed for its age-gender distribution for a ten year period. Identified gender-specifc age differences in culturally defined male and female genital manipulation practices. For example, infibulation, labial reduction, and clitorectomy practices, 4 peak age groups were uncovered demonstrating several possible intercultural relationships with these unique procedures, two of which were commonly engaged in quite recently within US facilities. The highest risk groups of American citizenship age females were found to be 1-4 yo female infants/children and 30-37 yo mid-life women, many or most of whom were surgically modified in a US setting. This methodology defined four high risk age groups for which specific intervention procedures may be developed.

Aug 2011–May 2012  

Research: National Population Health Age-Gender Studies related to Socioeconomically-linked disease and unhealthy behaviors: STDs

Evaluated ICDs for STDs and related UT or sex organ disorders. Demonstrates gender asymmetry for diagnoses, with F>M for most STDs and related UT problems. M>F for syphilis related clinical events, for both Early and Late diagnoses. Female related UT related problems like pyelonephritis normally associated with sexual activity demonstrated a distribution of cases across non-sexually active ages as well.

Jul 2011–Sep 2011  

Research: Regional ICD-based Incidence/Prevalence Disease Research of the US: ICDs evaluation

15-24 regions of the US were identified based on a review of Census Bureau, NCQA and other Federal standards. Regions were evaluated and compared with the rest of the country for statistically significant Incidence/Prevalence differences; 160+ diagnoses evaluated, including the following: anorexia, anorexia nervosa, RSV, heart failure, morbid obesity, diabetes, metabolic syndrome, HTN, DIC, Chronic Liver Disease, GERD, Fibromyalgia, PTSD, asthma, COPD, lower back pain, hemophilia, AMI, Ischemia, gall bladder disease, chronic liver disease, STDs, pyelonephritis, sickle cell, thalassemia, atrial fib, osteoarthritis, rheumatoid arthritis, crohn’s disease, ADHD, bipolarism (by degrees of severity), epilepsy (by subgroups), etc., etc.

Jul 2011–Mar 2012  

Research: The National Aging Population Study

New statistical method tested for evaluating ICD-related differences across different Age-Gender 1-year Age groups. Three ICD age-gender groupings were evaluated: diseases mostly present in 65+, diseases initiated in 45-65 age group and continuing to increase in prevalence until 75 yo, and diseases which demonstrate a rapid reduction in prevalence after 65 years of age. ICDs with Old Age specific onset include parkinsonism, emphysema, diabetic retinopathy, atrial fibrillation, hyperkinesthesia, some leukemias, brochiectasis, the various dementias, degenerative nerve disorders, renal failure and ESRD. Those with 45+ mid-age onset include Takatsubo syndrome, glaucoma, COPD, AMI, various prostate conditions, neuropathies, PAN, myasthenia gravis, tinnitus, lower back pain, psoriasis, menier’s disease, dupuytren’s contractions. Metabolic syndrome and numerous other early to mid-age onset diseases tend to display reductions in age due to mortality rates, and psychosomatic influences on these conditions. These include the well correlated diagnoses of obesity, diabetes, hypertension, fibromyalgia, GERD, IBS, Insomnia. Several disease with identical long term outcomes due to biological degenerative causes (early mortality) include chronic liver disease, heart failure, rheumatism. A number of age-limited diseases were also noted–those which demonstrate little to no prevalence as the population ages. These include fatal diseases, such as CLD, certain forms of heart disease, sarcoidosis, but especially migraine (65 yo cut-off).

Jul 2011–Sep 2011  

Research: Regional ICD-based Incidence/Prevalence Disease Research of the US: Age-Gender Modeling

15-24 regions of the US were identified based on a review of Census Bureau, NCQA and other Federal standards. Regions were independently evaluated for prevalence/incidence for 160+ common high cost diseases. Specific regions were found to have specific age groups clustering, with SE, NE, Upper Midwest, Central SE demonstrating statistically significant differences in age-gender distributions. One region demonstrated high numbers of retirees, two others high child-mother counts and relationships at the family/household level. The southern half of NE was found to have people close to retirement age bearing high I rates mimicking those of the older age group situated in the SE. This methodology proposed for use in regional disease monitoring techniques.

Jun 2011–Jun 2011  

Research: National Age-Gender Heart Valve ICDs Study

New statistical method tested for evaluating ICD-related differences across different Age-Gender 1-year Age groups. Three of the four heart values demonstrate gender symmetry and similar age prevalences. The fourth heart valve (Pulmonary) demonstrated a larger peak in newborn populations, with diagnoses continuing into adult age ranges.

Jun 2011–present  

Research: Disease and Destiny

USA · Beacon, NY

Data gathered from bibliography of same title (Judson Bennett Gilbert, 1962, 536p), a review of Surgeon General’s Index-Catalogue, Index Medicus, 1879-1960; 30+ illnesses identified as influential upon life accomplishments for 400 of 2265 individuals.

Jun 2011–Jun 2011  

Research: National Age-Gender Heart Valve ICDs Study

New statistical method tested for evaluating ICD-related differences across different Age-Gender 1-year Age groups. Three of the four heart values demonstrate no gender asymmetry and similar age range distributions. The fourth heart valve (Pulmonary) demonstrated a larger peak in newborn popualtions.

Jun 2011–Jun 2011  

Research: National Age-Gender Chicken Pox ICDs Study

New statistical method tested for evaluating ICD-related differences across different Age-Gender 1-year Age groups. Case distribution evaluated.

Jun 2011–Dec 2012  

Research: National Statistics for Culturally-bound syndromes

Integrative Population Health Modeling

Undisclosed National Health Database company. Extremely controversial project. Analyzed well over 100 million people health dataset for Culturally-bound syndromes and medical conditions linked to specific ethnic groups. Developed innovative approach to modeling these diseases, even though many are exceptionally rare and not often reported. Age-gender distributions for related ICD-9 classifications for these conditions were analyzed, and prevalence curves developed for individuals diagnosed with these conditions; developed a unique series of formulas used to compare 1-year age-gender distributions to theoretical ICD-9 assignment for condition for individuals with ages provided by electronic medical records. Statistically analyzed validity for this ICD-9 class based on other applications for same ICD identifier. ICD-9 distributions do not match reported case age-gender distributions. Syndromes for which ICD-9 codes could be assigned were evaluated, including SUNDS, Takotsubo syndrome, African Cardiomyopathy, Factitious Disorder, Pibloktoq, Uqamairineq, and Demonic Possession. See https://brianaltonenmph.com/gis/population-health-profiles/part-iii-population-health-application/special-topics/socioculturalism-and-health/

Jun 2011–Dec 2011  

Research: A new way to document and measure prevalence of shaken baby syndrome and other child abuse practices

Integrative Population Health Modeling Team.

Shaken Baby Syndrome and other forms of severe child abuse were evaluated for the youngest age group. The rates for regional dislocation of elbow were found to be extremely helpful regional indicators of local infant abuse procedures. Due to their physical diagnosis nature, elbow dislocations are more likely to be reported or recorded than child abuse procedures involving children < 3yo such as shaken baby syndrome and battered child syndrome. Statistics developed for this methodology match 2005 national findings. Prevalence rates measures for elbow dislocations graphed in 1-year ranges for more than 100 million patients of normal age distribution for the US working class population were more useful in defining regional differences than actual abuse related ICD-9 entries placend in electronic medical records. This methodology also allows for statistical evaluations to be made per 1year age bracket. Methodology was also applied to other forms of child abuse identified by ICDs. This methodology is a continuation of the research process developed for the National Health dataset evaluated since 2010.

Jan 2011–Dec 2011  

Research: New Technology-New Chronic Disease Management Techniques

Undisclosed employer/location. Integrative Population Health Modeling team.

The 1-year Age-gender population techniques developed were applied to several chronic diseases in order to more accurately define specific gender and age differences related to the planning of intervention programs. Specific one-year age peaks could be defined for certain chronic diseases suggesting that age groups to undergo preventive health practices are substantially different across genders (i.e. MS, many heart diseases, schizophrenia). Other ICD groups evaluated demonstrated smaller gender differences (epilepsy), and others no age related difference in gender related incidence-prevalence findings (diabetes). These age-gender pyramids can be used to develop a more targeted intervention program.

Jan 2011–Feb 2012  

Research: National Age-Gender Acute/Chronic Diseases Study

We typically consider acute diseases to be significantly different from chronic diseases. Acute diseases are at times considered a precursor to the more severe chronic disease state of similar clinical appearance. Age-gender analysis should demonstrate specific differences between acute and chronic disease distributions. A number of disease types were evaluated for this relationship. Some diseases like acute versus chronic pancreatitis demonstrate absolutely no statistically significant differences in age-gender distributions. Diseases with ICD codes defined in order to define states did demonstrate staging, such as the various levels of chronic renal, liver, heart and lung diseases. Acute versus chronic did not demonstrate these notable differences suggesting a difference in severity between the two. The possibility that acute and chronic diseases of the same organ state lack these differences suggests that age is a primary determinant of risk and severity, regardless of the cause for acute versus chronnic disease onsets. Causes are multiple, but tend to effect the human body around the same stage in life.

Aug 2010  

Research: Population Pyramids and Health

Undisclosed National Health Database Company. Integrative Population Health Modeling program. · Population Health Biostatistics. Developed tool for analyzing and modeling population age-gender relationship using moving window technique. Tested equations developed for pyramid comparisons and statistical analyses of N=1000 to 100M.

National Pharm/Public Health Industry

Oct 2009–Apr 2010  

Research: A new way to test for statistically significant differences between two 2D or 3D objects.

Created 2D/3D formulas used to compare two different land transects, profiles or 3D surfaces. Used this to design a way to model large population difference. Farmulas based on Idrisi Remote Sensing work. Tested for use in Human Facial Feature Recognition software; developed for use profiling places, mapping costs vs. people (gas, market industry); applicable to analyses of any graph or figure with a 2D profile or 3D surface feature. Invented series of statistical formulas for use in measuring statistically significant differences when comparing two different surfaces or profile features. See https://brianaltonenmph.com/gis/population-health-profiles/part-i-a-new-method/

Jun 2009  

Research: Automated Grounded Theory Applications for Outcomes Measurements

PIM · Biostatistics

Continuing Medical Education

Apr 2009  

Research: Design of a methodology for assessing Level 4 (clinical performance) and Level 5 (population health) impacts of Continuing Education programs targeting physicians, allied health care providers and health care administrators (GIS utilization)

Biostatistics, Postgraduate medical education

Denver, CO

GIS utilization methods were developed in order to initiate methods for assessing population health features in relation to areal population health information for a Florida health care system with a well-defined managed care members pool. State and county health data are assessed in order to determine overall regional population health features, Census block and block group data are assessed for use in monitoring possible impacts of service location and gender-age-ethnicity to specific population health needs for the study region. Primary subgroups with medical needs are identified, and specific HEDIS and non-HEDIS (i.e. NCQA) institutional measures were defined for use in testing whether or not population and clinical performance changes took place. Whether or not these changes are statistically significant is also assessed using 2×2 chi squared analysis. Changes brought about at the patient-physician level in relation to the topics focused on in CE programs are then quantified by a similar approach. The overall goal of this project is to design education programs that meet local population needs in such a way that their impact can be measured. This will improve the ability of local programs to satisfactorily meet the needs of the local population as required by their overseers. This population health GIS research method may be used to demonstrate the kinds of improvements that take place at the local level, but also be used to quantify the most effective intervention techniques to be used on a per population/per special needs basis. Additional measures were taken of non-local service-related needs and provisions, such as the use of local cancer programs by non-local members or outside patients. Whereas state and county data help provide a baseline value for use in comparing outcomes for this project at large scale regional levels, the best means for quantifying outcomes locally was found to be defining specific areas with measurable outcomes. These areas require significant population loads, may be more block-group based rather than block-based, and may require that baseline values for each region be determined before assessing the region for changes in outcomes measured at some later date. For the most part, all measures were made using methods previously accepted in other NCQA programs performed by outside information sources or providers. All analyses are carried out using the standard 2×2 chi squared methodology applied based on typical NCQA and internal QA measures standards. Sources for medical data for this study include state and county datasets, census and TIGER files datasets, US population health study outcomes, and local patient records accessed according to HIPAA standards, making use of an intermediary, sufficiently trained in this form of data gathering process in order to avoid IRR problems.

Jun 2008–Jun 2009  

Research: Improvements made in Survey tools for large populations

TMG · Biostatistics

Postgraduate Medical Education

Apr 2008–Aug 2008  

Research: Utilization of Sequential Timed Series and Segmented Data Analysis techniques for analyzing education programs and designing performance improvement activities.

Denver Health/TMG · Quality Assurance/Biostatistics

United States · Denver

Postgraduate medical education/Denver Health Managed Care

Apr 2008–Jun 2009  

Research: Improving Time-cost efficiency when implementing large population surveys. Mann Whitney/Kruskal-Wallis ANOVA predictive modeling techniques.

Biostatistics, Postgraduate medical education

Denver, CO

Tested the implementation of a Mann Whitney tool used to measure population change involving 5000+ respondent groups, with max group size = 33,000 for group 1 (pre) + group 2 (post) programs. Study demonstrated that surveys of 300 to 1500 are all that are needed to quantify population responses and measure the efficacy of an education program. Due to typical human response behaviors, researching large populations for responses does not demonstrate any significant change in improvements or overall outcomes based on the use of standard Mann Whitney and KW ANOVA pre-post measures. This was determined to be a phenomenon of respondent numbers and is highly dependent upon the ratio of response counts for the two survey outcomes. A ratio < 3:1 (#group 1:#group 2, or #group 2:#group 1) is the determining factor in measuring group changes, not absolute numbers once group 1+group 2>300. When ratios are <3:1 (or 1:3), variance in response patterns and statistical P (p) outcomes demonstrate greater changes in outcomes dependent upon small changes in population size. The minimal difference between a pre/post survey of 50 pre + post, with post responses ranging from <20 to 15,000 response counts with identical response patterns, demonstrated no difference in final conclusions drawn about the overall success of a program. Final averages may vary slightly, but conclusions drawn based upon final P (p) values do not. Variances in response patterns when ratios are <3:1 (or 1:3) become unpredictable, making this predictive modeling technique unstable and in need for adjustments in methodologies.

Jan 2008–Mar 2009  

Research: Predictive Modeling of Outcomes based on very low response counts.

Biostatistics, Postgraduate medical education

Denver, CO

Typically, educational programs with exceptionally low response patterns cannot be easily evaluated using standard pre-post analysis techniques. This review began with the question: can larger group sizes with identical theoretical outcomes be used to predict the failure or success of an educational program. Outcomes for approximately 20 programs were evaluated using base data (n < 40 for pre or post group). The outcomes for these theoretically identical programs with identical outcomes were then compared, based on increasing sizes for respondent populations. This demonstrated that identical response patterns duplicated for much larger populations can be used to predict a program’s outcome, assuming responses are representative of a typical human population and will undergo little change as numbers of respondents increases. (At a corporate level, this provides a better, more accurate outcome required for reports to grantors and education providers; at an academic level, this assumption is arguably problematic, and is dependent upon the homogeneity/homoscedasticity of human response patterns from one study population size to the next.)

Jan 2007–Mar 2007  

Research: An Evaluation of Pharmacy Services provided to High Cost Medicaid Choice Members

Denver Health · Denver Health Managed Care

United States · Denver, CO

Denver Health/Medicaid Choice

Apr 2006–Nov 2006  

Research: Management of High Risk Pregnancies

Denver Health · Denver Health Managed Care

United States · Denver, OR

Denver Health/Medicaid Choice

Sep 2005–Dec 2005  

Research: An Evaluation of the use of a local Smoking Cessation Hotline program used by Denver Health Managed Care members

Denver Health · Denver Health Managed Care

United States · Denver, CO

Denver Health/Medicaid/Medicare

Jun 2005–Aug 2005  

Research: Design of an Automated Text Mining Program using Standard and Professional Lexicons

Denver Health · Denver Health Managed Care

United States · Denver, CO

Denver Health/Medicaid Choice/Medicare/CHP+/IPH

Jun 2005–Jun 2006  

Research: Internal Data Acquisition and Information Resources Development Processes

Denver Health · Denver Health Managed Care

United States · Denver, CO

Medicaid Choice/Medicare/CHP+/Employee Health Insurance Programs

Apr 2005–May 2005  

Research: Design of an automated system for calculating statistical outcomes by comparing two datasets

Denver Health · Denver Health Managed Care · Denver Health

Quality Assurance · Denver, CO

Standardized projects typically require identical analytic steps to produce their final reports. Examples of such programs include the NCQA measures and reporting requirements for quality assessment of managed care programs, reviews of populations served by PPO and non-PPO (POS, FFS) health insurance providers, and the typical Medicaid and Medicare subsidized health care/health maintenance programs. Due to these standardized measuring techniques, the calculation process can be automated for most of these programs. This enables time spent to consist primarily of data entry and report writing processes. In theory, the use of an automated data processing tool or system frees up time for more careful planning, presentation techniques and final reports to be developed. This also provides additional time for the development of prevention programs, with the goal of improving future outcomes of your studies as required by Medicaid, Medicare, NCQA, and other institutional overseers, and strongly advocated by various gatekeepers and HEDIS measure monitoring agencies and providers. The development of this analytic tools consists of the following sections or worksheets: readme; dataentry; datacopy; counters; data processors/recoders; statistical analyzers; outcomes summary page (text generated information), pasted information, and final reporting page. The most important worksheet in this methodology is/are the analyzer(s) (more than one may be needed). This worksheet has to include the most basic forms of statistical analysis (all of which are automatically calculated) such as 2×2 chi squared, an Exp-Obs chi test analyzer, a 2 x n chi squared matrix format, a median test and Hake’s score calculator, a linest/slope analyzer if/when applicable, one or more t-Test and ANOVA pages, a matched pair producer programmed to recognize when this method may be used, Pearson’s and/or Spearman’s coefficient calculators, a KW ANOVA analyzer (if applicable), McNemar’s and Cochrane’s calculators, and sections devoted to standardized informative data such as means, standard deviations, max, min, variance, 95% dataset average, mode, etc., etc.; graphs are typically added at the beginning and ends of these reports or their appropriate sections. The purpose of the datacopy sheet is defined as a possible filtering, reassigned value, or reclassification agent. The report spreadsheet should be used to generate both a printable reporting page and an easy to use cut-and-paste display of information for inclusion into standard handouts that require this information at an institutional/company-based reporting level. This methodology is capable of cutting report development time down significantly, usually down to one-tenth the original work and time requirements. The use of this method provides significant improvements in project management-related analytic time commitments, speeds up productivity, and allows for continued updates and improvements in the work process to be made. In many cases, data entry may be undertaken by one individual, and reporting by another. The allows the analyst to spend more time further developing his/her research and analysis methodologies.

Apr 2005–Jun 2005  

Research: Design of automated data analysis system for Monitoring Managed Care Programs

Denver Health · Denver Health Managed Care

United States · Denver, CO

Colorado SSI/SSDI Medicare/Medicaid/CHP+ Managed Care Program

Mar 2005–Mar 2006  

Research: A Hexagonal Grid Algorithm for Spatially Analyzing Epidemiologic Data (GIS)

Community Health · Portland State University · Community Health

Portland, OR/Denver, CO

Traditional GIS grids make use of square cells, which have a nearest neighbor/proximity-induced error due to objects placed in the corners of each cell. To overcome this error, hexagonal grids are the best means to document space over specific locations when relating two underlying spatial features expressed as points. This spatial analysis technique was introduced by Walter Cristaller in 1933 (Die zentralen Orte in Süddeutschland. Jena: Gustav Fischer). By offsetting hexagonal grids and statistically manipulating these overlays, one can improve the resolution of the analysis method and approximate moving window or moving circle methods of spatial analysis. To produce a hexagonal grids algorithm, a specific series of recurring equations were used to define two series of nodes or centroids in alternating fashion. This project resulted in the development of a tool with which grid cell nodes and centroids can be defined based on predetermined cell edge size for distance plots, cell diameter/radius (for distance/area plots), or cell area (for areal plots). The result of this equation is the production of lat-longs required for the production of a hexagonal polygon grid map, that can be plotted over a research area. By incorporating the Theissen polygon equation into this process, centroids are converted into polygons and a final hexagonal grid is produced. Grids of various sizes were reviewed and applied to documenting the spatial distribution of toxic waste sites in relation to other point data such as census block centroids, public landuse/meeting sites data, neighboring site lat-longs, and cancer case data. By re-running this shapefile program 4 times one can produce several hexagonal cell grid maps that can be merged to form a much higher resolution end product. The spatial accuracy of this combined high resolution grid mapping technique was compared with resolution/spatial error of other traditional epidemiological spatial studies such as moving circle and moving window techniques. This sophisticated method of spatial analysis enables more helpful epidemiological studies to be performed without the problems attached to square grid analysis techniques or the limitations placed on users by moving circle/moving window programs. This type of control strengthens and fine tunes the outcomes of such studies and prevents the likelihood of error that can arise from other more traditional square grid mapping techniques.

Jan 2005–Apr 2005  

Research: Colorado Lynx Health and Ecology (GIS)

Arapahoe Community College · Geography · Arapahoe Community College

Denver, CO

ArcView 3.2/Spatial Analyst and ArcGIS/Spatial Analyst were used to identify best sites for future lynx releases. Techniques made use of local DEM-topographic information, climate and hydrogeographic maps provided by local data providers, EPA-provided vegetation zone patterns (arc, ras and grid) and NLCD maps, and datasets/databases developed to describe lynx-hare behavior and plant especiation ecologic relations to both lynx and hare ecology. The best sites for Lynx introduction were identified as portions of the midsouthwestern and midwestern high elevation portions of Colorado, and an isolated high elevation setting in the northeast section of Colorado. Several species of foraging crops combined with shrub and tree related sources for protection of hares and pasture edge montane settings were identified as the best locations for possible cohabitation sites.

Jan 2005–May 2005  

Research: Design of a monthly reporting system for 302 Population Health Measures

Denver Health · Quality Assurance

United States · Denver, CO

Denver Health Managed Care

Dec 2004–Aug 2006  

Research: Identification of Pre/Post-partum Diabetes patients for potential Risk Assessment

Denver Health · Denver Health Managed Care

United States · Denver, CO

Denver Health/Medicaid Choice

Jun 2004–Jun 2007  

Research: Denver Health Managed Care Population Statistics

Denver Health · Denver Health Managed Care

United States · Denver, CO

Denver Health/Medicaid Choice/Medicare Choice

Jun 2004–Jun 2007  

Research: Ambulatory Care of High Risk Asthma Patients

Denver Health · Denver Health Managed Care

United States · Denver, CO

Medicaid Choice Program

Jun 2004–Jun 2007  

Research: Cervical Cancer Screening and Follow-up

Denver Health · Denver Health Managed Care

United States · Denver, CO

Denver Health/Medicaid Choice

Jun 2004–Jun 2007  

Research: Patient Compliance with CDC Child Immunization Requirements

Denver Health · Denver Health Managed Care

United States · Denver, CO

Medicaid Choice program

Jun 2004–Jun 2007

Research: Diabetes Care and Prevention

Denver Health · Denver Health Managed Care

United States · Denver, CO

Denver Health/Medicaid Choice program

Sep 2003–Oct 2003  

Research: Identifying the source of an Aedes vexans Public Nuisance Swarm (GIS)

Portland State University · School of Community Health · Portland State University

Poughkeepsie, NY

In mid-August 2003, a public complaint was filed regarding a dense swarm of mosquitoes just outside the most populated portion of the largest city in the county. Inspection of the area failed to uncover the possible source for this public health nuisance. For remediation of this problem to commence, we had to document the source(s) of the swarm. As a result, traps were set approximately every 0.05 miles north, south, east, and west of the complainant’s residence, with the furthest traps situated about 1.25 miles to the south, 0.5 miles to the east, and 1.0 miles to the north (the river edge formed the western boundary of this research area). Approximately 75 feet to the west of the complainant’s residence was the Hudson River shoreline. After just two collections of trapped specimens (3 days into the study), a possible location for the source of this swarm could be proposed (the other side of the fence surrounding property owned by the city and monitored by subcontractees). Traps were then set around the immediate boundary of this property, resulting in the densest capture of Ae. vexans for the season (ca. 2000+ insects per day per trap). Field inspection revealed that the swarm was concentrated on a partially wooded setting, private property situated just east of complainant’s residence and downwind from some fenced off private property. A city sanitary officer was contacted and entrance to the source location obtained. Source for the swarm was still not immediately identifiable, but opening a mancover in the center of this property exposed an Ae. vexans larvae/pupae-rich stagnant water pool. Grasses growing in the adjacent field edge had a slime-like covering suggesting a recent spill of sewage materials from an old late 19th C storage container situated within the adjacent building (just uphill from the cleaning facilities that dump decontaminated water into the river). Simple bar plots and density contours on the map show Aedes captures to be statistically related to the distance from this site, verifying the source for this swarm.

Sep 2003–Apr 2004  

Research: West Nile Surveillance: The Wappingers Creek Watershed Study (GIS)

Portland State University · School of Community Health/Public Health · Portland State University

Poughkeepsie, NY

Approximately 26 miles of the Wappingers Creek watershed was mapped using ArcView 3.2 GIS. Along this creek, 20 trap site locations were set from 1999 to 2003. Due to distinct differences in upper versus lower watershed land use patterns, ecologic comparisons could be made between undeveloped and developed regions of these parts of the watershed. Outcomes were compared with a similar study engaged in along the Fishkill Creek. Species and number of mosquito captures were found to be 5 to 10 times greater in the lower portion of this study area than the upper portion; the highest densities of potential vectors were found halfway between the main river (Hudson River) and the main urban area (Wappingers Falls village). Comparing this with outcomes of the Fishkill Creek study, it can be concluded that broad floodplains with minimal slope change across a large area (1 mi x 1-2 mi) play an important role in vector species persistance and survival. Reasons for this relationship of surface topography to vector density have to relate to one or more factors. i.e. a) flat surfaces increase the possibility of tree growth and canopy maturation, b) flat surfaces provide the soil and topographic features needed for water stagnation and the puddling and wetlands development required by mosquitoes, and c) flat surfaces are reasons for increases in human population density due to human settlement behaviors, an ecologic process learned by mosquitoes which has impacts on future reproduction/egg-laying location processes. Unlike Fishkill Creek vector findings, the more urbanized Wappingers Creek setting consists primarily of Culex pipiens-restuans hybrid species and almost no Cx. pipiens. Until urbanization is replaced by farming rural community settings further upstream, this dominance in species patterns remains an important high risk west nile feature of the area. The Fishkill creek demonstrates a similar transition in species patterns, with Cx. pipiens, Cx. restuans and Cx. pipiens-restuans more naturalized in the lower heavily rural/sub-urban Fishkill Creek setting, converting to Cx. pipiens alone in the eastmost rural settings. In sum, the primary finding is: Culex pipiens-restuans favors urbanized regions, with species conversion to Cx. pipiens and some Cx. restuans in the most rural sections of the study region. The incidence of west nile positive findings in either host, vector or human populations may be directly related to this change in Culex species biodiversity.

Sep 2003–Mar 2004  

Research: The Fishkill Creek Watershed Study (GIS) for West Nile

Portland State University · School of Community Health · Portland State University

Fishkill, NY/Poughkeepsie, NY

Approximately 25 miles of the Fishkill watershed were mapped using ArcView 3.2 GIS. The study area was defined using a 1.5 mile buffer area on each side of the river; this distance was chosen because it approximated the maximum range for the immediate or terrace 1 floodplain region along this lower Dutchess County river. Analyses were performed linearly along the river, as close as possible to its edges, and as a 1 mile transect drawn across a southeastern flood plain section which included both developed and undeveloped areas (housing developments, roads, field, oak-maple woodlands, wetland, and marshland ecosystems). This data was superimposed on DEM and topographic surface (SRTM) maps, and areas below 500′ elevation selected for future analysis. IDRISI tools were then used to develop a Slope and Aspect map; this was used to define regions of high and low west nile vector activity risk. Assumptions made: high exposure areas are less likely to harbor vectors, low exposure canopied areas with slope <5 are most likely. All data was then imported back into ArcView and the final analysis completed using ArcView Spatial Analyst. Based on these initial steps, a risk map could be developed for use in identifying the best locations along the Fishkill Creek for total creek and floodplain transect studies. For the transect study, the following outcomes were obtained: 1) a trendline equation with Rsq = .998 for an exponential decay rate of vector species capture density based on trap productivity relative to distance from stream edge, 2) a trendline equation with Rsq = .953 for a linear decay rate of vector species counts based on trap productivity relative to distance from edge, and 3) a trendline equation with Rsq = .9999 for an inverse exponential decay rate of vector species biodiversity relative to distance from edge. For the linear study, a grid map was produced depicting risk across a floodplain surface based on 3D modeling outcomes. Further use of this map could be made by adding NLCD information to the project. Based on the NLCD legend, area class 33 (transitional) was highest risk when placed next to a waterway, pastoral fieldedge or deciduous/evergreen forest.

Aug 2003–Feb 2004  

Research: Grid and Raster Imagery Applications to West Nile Surveillance (GIS/RS)

Portland State University · Community Health · Portland State University

Portland, OR/Poughkeepsie, NY

Small area analyses of a 150m x 900m area (2 forest-based homesteading properties) were performed of 12 mosquito trapping sites, with positive West Nile virus test results found for animal hosts, humans, and/or mosquitoes in this location. Focus was on landuse history, NLCD GIS data, vegetation patterns raster imagery (Landsat, AVHRR-derived, and other sources), and results of field work done on local hydrologic and vegetation/plant ecology data. Arc-polygon-based basemaps, gridmaps, elevation data maps, and raster images were overlaid, merged and then converted to rasters (vec-ras conversion) with greatly improved resolution (<20 ft x 20 ft cells). This resolution was field-verified and the data then analyzed using IDRISI for identification of hydrophytoecologic systems, defined using non-supervised classification systems and supervised classification systems derived from field tests and photographs. Canopy/subcanopy and other vegetation features were related to surveillance findings and then correlated back to specific demographic, transportation, property line, and landuse data features. Seven vegetation areas were defined, enabling west nile ecology/vector-host activities to be related to NDVI-AVHRR-reflection based vegetation pattern information. Trend analyses were performed treating entire rasterized area like a 3D surface; this enabled high risk areas to be identified based on vegetation and demographic features. Species diversity and richness equations (IDRISI-based) were then attempted in order to relate vector activity to vegetation type (tree canopy) domains, with the goal of defining the most effective trapping locations and canopy requirements for high density vector sites. IDRISI was also used to define specific subgroups of these areas throughout the testing area defined by supervised classification methods. Steps taken in this analysis included resampling, reclassification, development of thiessen polygons for trap settings, biodiversity analysis, relative richness test, cluster analysis, subcomponent analysis of reclassed images, a texture analysis of foliage distribution for 8 classes of regions, development of linear, quadratic, and cuboidal surface models used to define disease/species trends for study area. Goodness of Fit measures were made of all trend modeling surfaces produced.

Jul 2003–Oct 2003  

Research: Field Investigation for Possible Vector(s) of a Local Malaria Case (GIS)

Portland State University · School of Community Health · Portland State University

Poughkeepsie, NY/Rhinebeck, NY

The onset of a malaria case was reported to County Health Department, resulting in concerns that a local disease nidus might exist. The source of the case was an international summer camp for high school and undergraduate college students from Western Europe, India, South America, Africa, the Soviet Union, and Asia. Field inspection revealed the most likely source for possible malaria vectors was a small circular pond/lake formed from a glacial ice melt several thousand years ago. This water body was considerably deep for its radial size (>15′ depth, bowl-like, and ca. 70 feet diameter). The entire water body was shaded by a considerable amount of Acer and Fraxinus tree cover. Larva inspection of the lake along the entire shoreline revealed several Anopheles species: in particular An. quadrimaculatus, which is fairly common to this New York setting. Traps were set on each of four shore line locations around this pond, and specimens were collected for shipping to Walter Reed laboratories. Malaria-positive samples were not identified, suggesting the local malaria case was brought to the state from the victim’s homestead in India. This was the second year a case of malaria was diagnosed in this summer camp setting.

Jun 2003–Aug 2003  

Research: A unique Urban Setting for West Nile vectors (GIS)

Portland State University · School of Community Health · Portland State University

Rhinebeck, NY

The documentation of a number of positive testing hosts (crow, corvus) and history of a local human possibly infected by local sources led to a review of the area’s urban setting where the most recent + testing corvus was found. Since there were no significant stagnant water sources, underground culvert pipes situated along the roadway were suspected. To test these sites, traps were set in and around the small urban setting, with larva testing performed throughout the city (central village area) as well. The predominant species in culvert and settling chambers were Culex spp., suggesting possible origination of local cases from this water source, which often was found to remain saturated during the warmest days of the season. This finding led to testing of all culvert sites in or near heavily populated settings and settings with high risk populations for the remaining part of the year. No positive testing vector populations were uncovered. The positive testing corvus specimens identified in this region have traditionally been considered fly-ins.

Jun 2003–Jul 2005

  

Research: Independent Monitoring of Care Management Activities

Denver Health · Quality Assurance

United States · Denver, CO

Denver Health Managed Care

Jun 2003–Jul 2003  

Research: Disease Surveillance related to a Positive Testing Human West Nile Case (GIS)

Portland State University · School of Community Health · Portland State University

Poughkeepsie, NY

One of the first documented positive testing human west nile victims in the county (2004) could not be linked by the epidemiologic surveillance team to a potential source for this west nile based on the travel history of the victim. This person (m >65 yo) had no history of travel and for the most part was homebound. To uncover or rule out probable immediate, local origin, a series of traps were set around the individual’s home. A small area map was developed and shapefiles produced of the home, yard and nearby landuse, drainage, and water features, using ArcView 3.2. This map was then used to observe and monitor the spatial behaviors of both hosts and vectors in this ecosetting. Six species of mosquito were trapped in the immediate area, with Uranotaenia sappharina (frog-dependent, non-human vector activity) and Aedes trivitattus found to be the predominant local species. Competition against the primary suspect carrier resulted in an uncertain outcome statistically, but suggests vector species biodiversity could have prevented the human infection from being of local origin. However, a pool of the possible vector species for this region, Culex (Cx.) pipiens-restuans, was found immediately adjacent to a woodlands swamp approximately 75 feet from the residence, suggesting possible transmission of this disease due to Corvus host-Cx. vector interactions. This specimen did not test positive for west nile and no positive testing culex species have since been identified.

May 2003–Mar 2004  

Research: Shoreline Distribution of West Nile-related Mosquito species along an Estuary (GIS)

Portland State University · School of Community Health · Portland State University

Poughkeepsie, NY

The Saltmarsh mosquito (Ochlerotatus (Aedes) sollicitans) is known to carry west nile in several urban regions situated along the Atlantic Coast near New York City. Whether or not this brackish water species resides further inland along the estuarine Hudson River, where west nile GIS studies were being performed, was uncertain to local public health and mosquito experts. For this reason, a GIS study of this aspect of west nile ecology was implemented. A series of traps were placed immediately adjacent to the 45 miles of shoreline along the Hudson River in Dutchess County. 43 traps were placed with the greatest distance between trap sites equal to 5 miles from its nearest shoreline neighbor; all traps for this study were placed with 0.25 miles from the shoreline; duplicate traps were set in many places to determine if small distance changes impacted species patterns in trapping activities. These traps had an average distance of 77 feet from the shoreline, with 7 significant outliers; each area had at least 2 traps set, one <25′ and the other >25′ from the shoreline. Fifteen highly successful test areas were found, with many of these areas bearing 2 or more sites in close proximity and with varying sun-exposure, surface microclimate settings. A total of forty-three trap sites were used for this study; trap types included CO2-black-light (85% of traps set and counted), non-CO2 gravid (12%), and a Faye’s trap (3%). Variations in trap locations most frequently tested include: 1) proximity to water surface (<25 feet and 50-100 feet trap placement), 2) presence/absence of field versus forest edge near water, and 3) transect-like trap placement of 3 or more traps situated from <25 to >500 ft from river edge along open space (for inland flowing swarm detection). The most detailed area used for this test also included use of a linear (north-south transect laid parallel to river’s edge) and a grid pattern for set-ups (approximately 20 trap sites set in a 0.25 x 1.25 mile area). RESULTS: None of these trap captures contained the brackish water species Os. sollicitans. Inland versus shoreline trap capture revealed a tendency for Aedes trivexans to reside more inland than Ae. trivittatus. Transect analysis resulted in the detection of several swarm patterns in shorelines adjacent to 9 urban settings. For one of these settings, a grid system had to be employed to monitor the local swarm activity.

Apr 2003–Jun 2003  

Research: Oregon State Childhood Immunization Program: Reporting format, testing, and utilization

Oregon Department of Human Services, Public Health Division · Childhood Immunization Program

United States · Portland, OR

Oregon State Government

Apr 2003–Apr 2004  

Research: Applications of Photometry to West Nile Surveillance (GIS)

Portland State University · Community Health · Portland State University

Portland, OR/Poughkeepsie, NY

A hand-held quantum meter device (mfr. Spectrum Technologies) was used to measure sunlight penetration of shrub and forest canopies (photosynthetic photon flux) with the goal of relating light penetration features to vector activity. All 183 sites (trapped 2000 to 2003) were ecologically surveyed using a standardized 3 page form. Overall qualitative data entries focused on weather, temperature, humidity, hydrologic, and topographic features. Quantitative data focused on vegetation counts and photometric readings. Sites were then grouped/reclassified based on temperate, vegetation and canopy features for comparison of photometric readings in relation to trapping activity. Sites with >600 uJoules (uJ= mmole per m per sec) represent fully exposed areas with ranges of sunlight varying from 600 uJ/s (cloudy skies) to 1500 uJ/s (summertime midday, overhead sunlight, no clouds); typical sunny days produced readings ranging from 900-1200 uJ. Sites with <30 uJ are typically forest floor/subcanopy (i.e. conifer, heavy deciduous settings), with photometric readings as low as fluctuating 2-5 uJ at ground level (<2′ elevation above ground surface). Productive sites were required to have <300 uJ, with partial (speckling) to minimal light penetration (20-50 uJ); the most productive sites ranged from 30 uJ to 200 uJ. Sites with <20 uJ produced little trapping activity and are perhaps non-productive due to need for vectors to migrate outward into more open areas at dusk and dawn for mating and feeding activities. In terms of methodology: all measures were made using several sampling techniques. Both grid (5’x5′ cell) over a 15-25 foot surrounding area, and centroid-circle (var. 6-12′ radius) pattern techniques were employed. During a review of this data, the use of centroid data alone for correlation with species type and counts was found to be the least reliable method based on correlation matrix analyses of light measure:vector species counts. However, combined centroid-circle data was found to be fairly reliable, and was only surpassed slightly by correlations made using surrounding circle data alone. Even though grid data was also effective, the larger number of measures required to perform this type of measure, and the impact of surrounding vegetation and landforms of data gathering techniques, made it a less applicable and less reliable as a field testing technique. In several cases, transect (linear) measures were also taken from full-exposure to protected area to test out their usefulness. These outcomes were found to be very unreliable, providing little to no further insight into overall vector activity and ecologic features. Second finding: several species types were found to favor high light exposure regions (>450 uJ areas); none of these are known to be west nile carriers.

Jan 2003–Jul 2010  

Research: Depicting and Mapping the Evolution of Plantae with ArcGIS

Portland State University · Chemistry/Geography · Portland State University

Portland, OR/Denver, CO

GIS was used to relate environmental and human/biogeography to taxonomy, evolution and secondary-tertiary metabolite chemistry. Spatial relationships are drawn between climate, topography, landscape patterns, hydrography, geomorphology, especiation, population density, phytochemistry, ethnobotany, and the history of plant utilization by nature and mankind. Reviewed more than 250 categories of plant use, based on 76 primary-secondary chemical pathways producing 300+ major phytochemical/ethnobotany/pharmacology groups. A basemap of the evolutionary tree was then related to traditional geographic basemaps of the study regions. A method was then developed and tested for automatically superimposing the evolutionary tree with ecologic base maps for research-related uses in the lab/office setting.

Oct 2002–Apr 2004  

Research: Density and clustering of dead crows in relation to demography and landuse patterns (GIS)

Portland State University · School of Community Health · Portland State University

Poughkeepsie, NY

To differentiate the spatial distribution of infected dead crows (west nile hosts) and uninfected dead crows, the density of crow sitings, reports and test samples gathered were evaluated using moving window point count and kriging techniques. Concentrations in heavily populated urban-suburban regions were found to be less likely to be spatially associated with positive species- or host-test outcomes than concentrations related to certain low population, rural/ecologic (mostly wetland) settings (Chi sq > 3.84, p < 0.05). This methodology made use of ArcView 3.2 Spatial Analyst in combination with several ArcAvenue extensions.

Sep 2002–Sep 2006  

Research: A Transcendentalist Interpretation of Epilepsy

Portland State University · Geography/Public Health · Portland State University

Complementary/Alternative Medicine Special Interest Group · Portland, OR

What does transcendentalism have to do with epilepsy? Transcendentalism and transcendental beliefs form a basic part of the mindbody healing tradition. Documented causes and links between epilepsy, seizures, seizure control and alternative methods for seizure prevention such as biofeedback, suggest the application of certain aspects of neotranscendental thinking to the control of ongoing epilepsy may be influential, if not healing. In transcendentalism, one blames the psychological consequences of “bad health” on improper individual experience and its resulting thought processes, emotional consequences, behaviors and practices. In a transcendental sense, the lack of flexibility in establishing one’s paradigm about the health state, itself, becomes a part of that illness experience and as a consequence begins to dominate in eliciting the changes to survive with epilepsy, much less any other chronic condition. As a consequence, one’s future health experience and health status depend on one’s own belief system regarding illness and its meaning. This interpretation in turn not only helps to explain why the epilepsy experience becomes more predictable and frequent at times, it also explains how and why mindbody behaviors utilizing emotional, mental, spiritual and psychic triggers can be effective at laying new paths to reduction in seizures. Ultimately, for one to deal with such a state, the “illness” has to become less a condition of the brain and body as regular medicine likes to interpret it, and more one of mind, brain, and the resulting human experience. This review of transcendentalism relates both the Pavlovian-like (perceived risk), biopsychological interpretations to the more community-social Eriksonian interpretation of illness as an important part of the life experience. At times, chronic conditions, states, illnesses and disease can be interpreted as an important part of the human experience route for one to take, pass through, and then leave behind as a part of the past. Unfortunately, not many people with chronic afflictions like epilepsy interpret their state of being in this fashion within western society. This transcendental belief model is not simply the practice of traditional transcendental practices popular since the 1960s. Rather, it is a new form of transcendentalism, in part defined by Eriksonian writers, the primary goal of which is to better define the different stages in life one goes through and succeed in taking those routes. By passing through these stages and at some point transcending the normal life practices, one is better prepared to experience a potentially lifelong illness. Or better yet, by experiencing whatever positive long-term outcomes come your way due to this medical state, such an interpretation of managing and eliminating a potentially long-term condition like epilepsy becomes possible. In contemporary medical, epidemiologic and public health journals, this statement is supported by numerous articles published on epilepsy and the “learned hopelessness” hypothesis for seizure-linked depression cases. By interpreting such experiences in all other aspects of epilepsy in this fashion, one’s life can evolve into an example of exceptional human potential experience, rather than an example of learned hopelessness or helplessness.

Sep 2002–Jul 2003  

Research: Classification of West Nile Mosquito Trap Sites

Portland State University · School of Community health · Portland State University

Poughkeepsie, NY

More than 100 sites were defined for mosquito trapping by May 2002. A survey tool was developed for describing these sites and then applied to new sites established during the first half of the trapping season (May to October). This tool was improved slightly and then used to document the chief human and natural ecological features for the remaining sites trapped since 1999/2000. By the end of the season, approximately 120 sites were reviewed, mapped and evaluated using ArcView 3.2 GIS. This practice of site surveying and mapping was continued throughout the follow trapping season, resulting in 183 sites by 2004. This survey tool collected information regarding land use activities, neighborhood/local demographic patterns, proximity to water body or stream and description of this feature, a local comprehensive vegetation survey (ecosystem type, plant lists by genus and species for all groundcover, medium height to tall herbaceous, shrubs, young trees, crown/forest cover trees, tree canopy descriptions and estimated height, degree of sun-exposure/shadiness, land surface/topography type, and local urban setting type, the type of property/landuse the trap was placed on, trap types used, and reason(s) for selection of site for trap setting. Photographs were taken for each site. Major classification of site type and site selection processes resulted in several classification systems with site types defined by overall landuse, overall population density, overall ecological setting and primary reason for selection of location. Examples of reasons given for each site selected, in relation to this classification system include: potential +testing vector site, dead crow site, +testing dead crow site, potentially +human case site, crow migration/gathering site, proximity to waterbody/wetland, proximity to confirmed larva site, proximity to other trapping site, proximity to +test site, proximity to specific high risk landuse (i.e. livestock/horse farm) area, proximity to specific high risk community (i.e. retirement center), adjacent to urban (heavily populated high risk) area, proximity to dumping site (with high number of breeding receptacles), follow-up on complaints site. Specific site types had high correlations with species-specific trap productivity, in particular all river- and streambound species and several woodland/waterbody-specific species. Some correlations could be found for the west nile vector species (esp. Cx. pipiens-restuans) and land use/trap site type. An informational database of all of this site classification information obtained from the survey, includes genus and species specific plant ecology information, was developed for linkage to future GIS activities and submitted to the local epidemiologist GIS expert.

Aug 2002–Jun 2003  

Research: Identifying a positive testing vector site based on positive testing host data (GIS)

Portland State University · Community Health · Portland State University

Poughkeepsie, NY/Portland, OR

Late in 2002, a series of positive testing hosts (crow/Corvus sp.) were found focused within a five mile area. Due to disagreements regarding the source of these host deaths, ArcView 3.2 was implemented with the goal of identifying a positive testing vector source. To accomplish this, aerial photography was obtained of the suspected region, and numerous traps set using positive host sites to define the boundaries of the study region. Trap information was evaluated spatially and a weighted centroid used to define the most likely site of origin for the positive testing species; this centroid was first based on counts of the 4 most likely vector species captured (Culex pipiens, Cx. restuans, Cx. pipiens-restuans, and Aedes japonicus), and later redefined based on the weighted centroid for two possible positive testing vector species (Ae. japonicus and Cx. pip.-res.). Traps were set as close to the wetlands area as possible, resulting in trapping of the first positive testing vector species (Cx. pipiens-restuans). This region was then treated in accordance with state requirements (Bacillus thuringiensis containing corn granules). During the subsequent spring, retention of infected members of the mosquito species through successful overwintering led to documentation of the first and earliest positive testing site for the state, demonstrating the possibility of continued survival of infected species within the local environment. This was followed by reapplication of the Bacillus thuringiensis biological treatment.

Jul 2002–Dec 2004  

Research: Applications of GIS to matching SIC data with Toxic release site-related chemical release data (GIS)

Portland State University · School of Community Health · Portland State University

Portland, OR

Utilizing chemical and site chemical release dataset produced for all Confirmed Release toxic release sites in the state of Oregon, Standard Industrial Classification (SIC) data was used to compare and reclassify site chemical release history for correlation of chemical type and toxicity, and degree of carcinogenicity with particular SIC-derived reclasses. 450 sites were evaluated, resulting in more than 200 unique SICs; these SICs could be reclassified into 45 chemical release patterns based on the listing of chemicals and chemical types for each site. Some sites with significantly different SICs nevertheless had nearly identical release patterns (i.e. gasoline or petroleum product spills). Other SICs of similar range in value could be reclassed into a single group due to similar need for chemicals in their industrial processes (i.e. many secondary wood product manufacturers, such plywood/lumber manufactured products versus laminated/particle board industries). Still other classes which seemed related upon first glance (electronics vs. computer electronics, or raw wood/lumber industries vs. pulp/paper industries), were provided with different SIC reclass ids due to distinct chemical differences. A flowchart and table defining the reclass methodology was developed and then applied to all of these sites. Using this reclass method, site chemical data was compiled and each chemical type reclassified into several different chemical grouping methodologies (an example of this classification into groups: simple organics (simple solvents), simple inorganics, metal-derived products, combined organic-metals, benzenics, phenolics, halogenated benzenes, polycyclic aromatics, and undefined hydrocarbons, gasoline and petroleum products). Other classification systems broke the major groups into subcomponents (i.e. petroleum product type as stated by EPA information). Bar charts for each site could be mapped using these classification systems, producing maps with site type and location and a bar chart depicting amount of toxins released for each given site placed directly on the map. This enabled a site selection process to be developed, for each major subclass in order to correlate site chemistry and toxicty data with given SIC classes. This reclass data was also averaged out to produce and average release type and amount per site, data to be related to sites with known SIC information but no known or documented chemical release history. A similar methodology was then applied to site with unknown chemical history, by relating documented paper industry-release data in the studies CRI sites to other similar SIC reclass sites (i.e. paper-industry sites) in the state lacking adequate chemical release information. The different SIC classes were compared for reasonable outcomes, with some SIC reclass systems being nearly foolproof and other SIC reclasses demonstrating little statistical validity to the correlation. These SIC “signatures” (bar charts) for each site could be mapped to predict possible exposure histories for given areas with unknown release history, based on the reclassified SIC id assigned and related chemical signature linked to each site. This was later used to identify those areas most exposed to specific chemical groups or compounds, such as simple benzene exposure, benzene-derived phenolic compounds exposure, halogenic aromatics chemicals exposure, heavy metal exposure, organic metal (esp. mercury) exposure, polycyclic aromatics group exposure, and general petroleum products exposure. Three equations were developed to assign a numerical value to site toxicity based on this chemical profiling methodology.

Jun 2002–Aug 2002  

Research: OIHM: A Complementary/Alternative Medicine (CAM) Adult Education Program

Portland State University · Community Health · Portland State University

Portland, OR

Report title: OIHM. An ethnographic study of an Adult Complementary Medicine Summer Camp Program. Combined Quantitative/Qualitative Analysis and ethnographic study research methods, documented administrative history of this historically important adult health education/health promotion program; final review included economic, employment, financial history and success of camp, npo related review, demographics/student population features review, faculty activities and demography, overview of the teaching contract process, teacher pay process/amounts, and future income projections, and overall local impact of this highly popular $5M/year CAM-promotion program on the local community.

Jun 2002–Sep 2002  

Research: The Reconstruction of Roget’s Thesaurus into a Lexicon for Text Analysis

Portland State University · School of Community Health · Portland State University

Portland, OR

A scanned, electronic text version of Roget’s most republished edition was imported into Excel and modified to produce a lexicon applicable to GIS and Quantitative/Qualitative Data Analysis tools. Roget’s classification system was retained, with slight modifications in groups names in order to clarify and improve research utilization of this database. Several reclassifications of word data are performed with the goal of improving applications to health-related text content analysis activities. This is accomplished using non-supervised and supervised text content analysis systems, open and closed classification systems, hierarchical and nonhierarchical review methods, weighted analysis scoring techniques, and phraseology/relationships extraction review methods.

Jun 2002–Jul 2002  

Research: The Role of Community in the Development of Cancer Screening Programs

Portland State University · School of Community Health · Portland State University

Portland, OR

Project Development, Description, Budgeting, and Grantwriting. A method for implementing breast cancer and prostate screening programs by means of community involvement. Purpose: improve social awareness of these two gender-related cancer screening issues which are often underutilized or their screening activities underpracticed by the general public.

Apr 2002–Sep 2003  

Research: Development of Landuse algorithms for SPOT images (GIS/RS)

Portland State University · Geography/Community Health · Portland State University

Portland, OR/Poughkeepsie, NY

Algorithms play an important role in satellite imagery analysis. SPOT images differ from traditional Landsat images in that they consist of three bands and a panchromatic. This makes algorithms related to Landsat images (4, 6 and 7 bands, and visual color) less reliable for application to SPOT images. Several techniques were developed using the IDRISI program in order to strengthen the applications of LS algorithms on a SPOT image of Portland, OR. Techniques for differentiating dark water surface and dark manmade land/building surfaces were developed, followed by the application of supervised classification techniques in combination with specific formulas pre-tested using a collection of 1976 to 1993 Landsat images.

Apr 2002–Apr 2004  

Research: Transect Analysis of Elevation-related Mosquito Population Features (GIS)

Portland State University · School of Community Health · Portland State University

Poughkeepsie, NY

Two of more than 80 trapping areas used for West Nile Surveillance were identified that contained the following topographic features: proximity to large or major tributary (stream >20 feet across), neighboring pools, marshes, swamps and/or wetlands, significant or complete canopy coverage, significant changes in elevation (slope >15 degrees), and significant, continuous trap production. One site was located next to a large meandering river, situated in a large woodlands area (>10 mi across in one or more directions), and between two sizeable rural communities (one on each side of the river). The other site was situated in an area with steeper terrain, a more dispersed community with houses adjacent to the water on just one side of the stream, and evidence for numerous crow deaths with at least one specimen testing positive for west nile antibodies. Transects led from riveredge to mountainbase, and up the terrain to the final hillcrest or first predominant mountaincrest, each approximately 300 feet elevation above the water surface. Traps were set approximately 30 to 50 feet apart by foot, with elevations changing approximately 15 to 30 feet in height between neighboring traps. Traps were set at least twice a week in late July, August and early September. Speciation differences were notable between low elevation and high elevation traps. Aedes trivitattus was dispersed throughout study region, with Ae. vexans and Culex pipiens-restuans seen occupying upper terrace ecosystems, in level settings, not close to the streamedge. The results of this GIS were mapped using a DEM, to demonstrate pocketing on land surfaces associated with vector pooling places. Uranotaenia sappharina, a frog-dependent species, could be found both on stream edge and specific points away from the stream edge. Anopheles punctipennis preferred sites on hills, away from stream edges.

Jan 2002–Apr 2003  

Research: Utilization of OTC Nutritional Supplements by a local Geriatric Population

Portland State University · School of Community Health · Portland State University

Portland, OR

Combined Quantitative/Qualitative research. Six introductory OTC/CAM classes provided to 55+ yo social group devoted to aging and health. Students assisted in development of group survey; results analyzed. A review of 2000 to 2002 advertisements for OTC products found in popular culture/alternative medicine trade magazines was then carried out. OTC supplements were reviewed by companies and applications based on biologic system (NS, GI, renal, endocrine, psych, etc.), popular topics (aging, cancer prevention), and specific disease types (diabetes, joint disease, CHF). Groups surveyed include a focus group (>65 yo) and several special interest groups (50-70 yo OASIS students). Outcomes presented over several weeks as part of 6-week program.

Jan 2002–Jan 2010  

Research: Transformation of Common Belief

Portland State University · Community Health · Portland State University

Portland, OR/Denver, CO

The evolution of medical and pharmacological beliefs, theories and traditions, in relation to the pursuit for the best regimens pro temp. Different cultural and knowledge-based settings provide different reasons for the acceptance or the refusal to accept a given health-related claim. Whether or not an herbal medicine is adopted for use depends solely on scientific literature and the publishing/dissemination of a theory for action considered credible to various populations. Scientific reasoning form an important part of this belief, even though the science is later found to be inaccurate. Many of the current reasons for therapeutic effectiveness assigned to herbal medicines are based on similar reasoning and social or professional acceptance patterns. The changes in reasoning, logic and professional/scientific theory underlying professionally and socially accepted remedies are reviewed, from 16th century reasoning to contemporary 21st century reasoning.

Jan 2002–Aug 2002  

Research: The Ecology of leukemia in Oregon (GIS)

Portland State University · School of Community Health · Portland State University

Portland, OR

The state’s database of reported leukemia and lymphoma cases (ca. 2500 and 1500) was address-matched and mapped using ArcView GIS 3.2. Unmatched cases were then assigned true addresses or US PO box location based on database address information. These cases were reviewed for clustering by major class [leukemia (aml, cll, cml, aml, etc.) vs. hodgkins/non-hodgkin’s lymphoma], all 5-digit disease classification code-related subclasses, and by child/non-childhood cases information. Temporal relationships were not reviewed due to short lifespan of database. Clusters were identified using demographic (census block and block-group levels) information, isoline mapping techniques, varying Gi-related cluster analysis techniques, spidering and monte carlo statistical modeling. Cases were related to Superfund, superfund applicant, confirmed release and non-confirmed release sites information provided by EPA. Site data was analyzed for toxicity patterns possibly related to case clusters.

Jan 2002–Apr 2002  

Research: B.I.T.E.: Better Intuition Towards Eating (An SES-based Nutrition Education Program)

Portland State University · School of Community Health · Portland State University

Portland, OR

Program design with letter grant. Target: Low Income Hispanics population. Health Education program based on the Transtheoretical Model for Human Behavior. Designed a 15 month social services program to be administered in a satellite town/city in Mid to Northwest Oregon. Estimated Cost: $225,000. Key Words: Socioeconomics Status (SES) and Health; Dietary restriction and Changes; Modified Traditional Hispanic Diet; Reduced Food Costs.

Jun 2001–Aug 2001  

Research: Identification and Ethnobotanic study of a Mohegan Shaman’s Sacred Site

Portland State University · Chemistry/Community Health · Portland State University

Portland, OR/Rhinebeck, NY

Local ethnohistory stories resulted in the identification of a shamanic site used as recently as the early to mid 1700s by one or more Mohecan groups. The unique geomorphology and glacial till content of this site suggests it existed at least as far back as the end of the most recent glacial period in New York history (ca 4000-6000 yrs ago). Due to its island community-like nature, the ecology and lack of human disturbance of this site allowed its eighteenth century vegetation features to remain a part of the local ecology. Several unique if not rare plant medicines mentioned in mid-18th century botany notes by Jane Colden were found on this site. Land ownership history of this sacred site was determined (area protected due to wetlands location). The unique underlying topographic-, and philosophical reasons for this use were documented and photographed.

Jun 2001–Jul 2003  

Research: Development and Testing an Algorithm used to define risk and toxicity of a Chemical Release Site (GIS)

Portland State University · School of Community Health · Portland State University

Portland, OR

NIH, CDC, AMA, American Cancer Society, CERCLIS, NIOSH, and EPA have each developed their own unique methods for evaluating chemical history, chemical release safety, site toxicity, human health risks, animal risks, and carcinogenicity for each chemical release site. For each of these measurement methods, the numeric value assigned to a site is based on release history and site chemical testing outcomes. Each of these algorithms serves to assign a numeric value or ranking to a site, meant to be interpreted as a risk indicator. For this study, a series of new algorithms were developed, and used to produce an integer value designed for use as an indicator of site toxicity and carcinogenicity based on each of these separate measurement methods and chemical database review for each chemical and release site. With this formulas, sites could be evaluated based on chemical class, subclass, toxicity of subclass, carcinogenicity of subclass, carcinogenicity type based on EPA/NIOSH assigned risk level values, method(s) and amount(s) of exposure, and likelihood of uptake and biologic breakdown following exposure. In the end, these three equations were developed for use in reevaluating each site for subsequent comparison through the use of GIS. Each formula serves as a sensitive indicator for a particular set of environmental, toxicological, or carcinogenecity features. The purpose of developing these equations was to be able to more fully assign a risk value to a given site and relate this risk value to given human demographic features, local environmental features, and EPA, NIOSH and CERCLA-assigned risk values already in use for each site. The entire state’s chemical data and site severity indices were then compared with national statistics of the same provided by CERCLIS. With this methodology, the most toxic sites, based on a numeric classification system could be identified and mapped for later correlation with particular cancer types. Since each of these points has an assigned chemical type and risk datum, a contour/isopleth map could be developed for each chemical type and risk level for each urban region/industrial and the entire state.

Jan 2001–Mar 2001  

Research: Spatially Defining High Risk areas for West Nile (GIS)

Portland State University · School of Community Health · Portland State University

Poughkeepsie, NY

Population features were related to trapping locations. Each trap site used from 1999 to 2002 was revisited and surveyed for several demographic, landuse and vegetation-related features using a 3-page standardized ecologic survey tool. Census block data was used to locate high risk group population clusters defined as M/F age >65. Through the use of business directories, site visits and travels to trap sites, other high risk sites were identified and related to results of trapping and dead crow clustering patterns. Based on local features, sites were identified as one or more of the following for crow behavior: roosting/waypoint, aggregate/mating, nesting or feeding sites. More than 40 types of demographic/topographic features for these sites were identified and catalogued. Census blocks/residential settings with high concentration of 65+ residents were identified. Highest risk areas were established based on landuse patterns, positive vector/host test results history and density and actual human case histories.

Sep 2000–Dec 2000  

Research: Socioeconomics history, health, and cultural status for several Southeast Asian populations in Portland, Oregon

Portland State University · Community Health · Portland State University

Southeast Asian Health · Portland, OR

Community health; cultural anthropology; epidemiology; socioeconomics. A review of community activities engaged in by local in-migration Cambodian and Vietnamese populations. A survey (30 questions) was developed for on-campus distribution to Vietnamese, Cambodian, Laotian and Hmong students (Vietnamese in-migrants of indigenous Chinese descent) and then redistributed in a traditional Laotian church setting. Focus group activities were engaged in at a Laotian cultural dinner gathering; six Laotian individuals (age 20 – 30 yo, bilingual) and one Laotian MSW group leader were interviewed for inclusion as part of the ethnographic research portion of this project (Qualitative analyses). Survey data was then analyzed using SPSS. Other qualitative research data was analyzed using closed and open methods for text content analysis. Cultures were compared; differences in socioeconomic history and population health histories and status (esp. TB and SUNDS histories) were discussed. Several unique culturally-bound syndromes and/or medical concerns were uncovered.

Sep 2000–Apr 2001  

Research: Breast Cancer Screening Programs and Socioeconomic Status (GIS)

Portland State University · School of Community Health · Portland State University

Portland, OR

Statewide demographic data and breast cancer screening, incidence, prevalence and mortality data were mapped using standard ArcView 3.2 Geographic Information System (GIS). 2000 Demographic data was evaluated at a block and block group level. Some areas were evaluated using median income data and GINI testing. Many areas had to be identified or verified as low income/high risk based on additional field work and additional local demographic research and knowledge. Spatial analyst was used to define frequencies of screening activities in given regions, including numbers and types of people screened, and type of facility/program providing the screening program. This was then related to areas where severity of cancer type and related mortality outcomes were found to be significant statistically and/or administratively. The two highest risk regions were defined for the state: a heavily populated urban setting in the Northwest corner of Oregon and a rural population located in the central-east portion of this state.

Sep 2000–May 2001  

Research: The evolution and history of MindBody health traditions

Portland State University · School of Community Health · Portland State University

“Transformation of common belief” (TOCB) is the hypothesis that states a culturally- and/or personally-defined belief system is responsible for a large part of the medical system we believe in and plays an important role in forming the psychosomatic and scientific bases for many of the healing processes we adhere to and live by. This TOCB concept is commonly taught in the current pharmacology/pre-pharcmocology and medicine/pre-medicine/pre-allied health series of classes provided by this university. TOCB is reviewed across numerous cultural settings and time, focusing on the tradition and philosophy of healing practices and the sickness/disease experience based on cultural interpretations. the following steps were identified as essential components of this evolutionary process. The evolution of the ancient Greek to Renaissance ideas of the four humours and great nerve (sympathetic nerve) theories could be related to later evolved theories focused on autonomically-and emotionally-induced somatic changes. These were again transformed into Colonial Science interpretations based on Boerrhaave’s teachings with an increased emphasis in emotions and beliefs, to early American emotions and nerve energy-derived theories (brunonianism), to redefined vital force/energy field based theories of the 1800s (“galvanic” and “electric” vital forces), early to mid 1900s (autonomic and psychosomatic), and modern theories (electric field, psychoneuroimmunological, quantum energy). This study and resulting course teachings trace the history of acceptance of acupuncture and other alternative ideologies into Western medicine, the history of the influence of epidemics on increased social acceptance of alternative medical beliefs, and the history of refinement of these theories due to scientific discovery.

Jan 2000–May 2000  

Research: Applications of 3D modeling of Watersheds to Environmental Disease-related Risk Assessment Modeling

Portland State University · Geography · Portland State University

Portland, OR

DEMs were used to develop algorithm/formula needed to produce an artificial land surface mimicking the DEM model. Purpose of project: develop a way to measure waterborne disease and predict high risk areas based on an ever-changing land and water surface lacking constant elevation above sea level features. IDRISI GIS was used. A Remote Sensing Algorithm could be developed by a series of ras-vec/vec-ras conversions performed in order to mimic linear patterns across a grid/ras elevation surface. Each grid cell of the former linear object (river elevation) was related to tangential contours and specific heights above nearest water level defined. regions for exposure to waterborne disease were defined based on elevation above most proximal portion of river, not absolute above-sea level elevation data. This was related to riparian disease ecology and local wetlands/peririparian ecology and local environmental chemical features (esp. soil) in order to define most probable locations for microorganisms to be naturally established. Focus was on specific salinity and pH requirements of Asiatic Cholera, but ecologic requirements for other important waterborne species were considered as well such as Vibrio parahemolytica and Salmonella intermedia. Resulting maps/images defined those locally populated regions most likely to experience initial exposure to disease and their satellite communities most likely to be exposed, in sequence. Hierarchical and nonhierarchical maps and flowcharts were developed, demonstrating the flow of triggers related to disease migration and the various natural and human ecological reasons known to exist for disease onset or return.

Jan 2000–May 2001  

Research: The Role of a New Age Religion in Community and Individual Health

Portland State University · Community Health · Portland State University

Portland, OR

Combined qualitative/quantitative research project. Key words: Psychosomatic medicine, complementary/alternative medicine, faith healing, mind-body healing, human potential. Identified local church group highly devoted to alternative medical traditions and beliefs, and interviewed church leader, group members and elders to learn reasons for participation in this New Age Christian group.

Jan 2000–Dec 2002  

Research: Portland State University

Portland State University · School of Community Health

USA · Portland

Jan 2000–Jan 2003  

Research: A Traditional Geographic Interpretation of Epidemiological Transition

Portland State University · Community Health · Portland State University

Portland, OR/Denver, CO

Merging traditions: Demographic and Epidemiological transition theory and changes in landuse patterns defined by geographers, 1930 to 1970. Approximately 2500 articles (most published in medical magazine/journals ca. 1780-1880) on medical geography, medical climatology, medical topography, etc., were reviewed, analyzed and catalogued regarding the various geographic reasons provided by authors for disease and epidemics prior to the recognition of the “germ” theory during the late 1880s/1890s. This microbial theory-based reasoning was found to be preceded by numerous theories of similar intent, ranging from the description of animalcules to other microorganisms also noted globally in numerous medical writings and texts (ca. 1790-1850). Primary physical geographic reasons for diseases were also documented and found to be quite numerous within US borders and across all Eurasian cross-cultural boundaries. The 19th century Soviet Union influences on this epidemiologic topic was found to be most impressive, although not well recognized in modern health geography writings. This is supported by the sizeable number of articles and texts cited in the late 19th and eaerly 20th century medical bibliographies published by the Surgeon General’s office. Soviet writings constituted in one of the largest collections of articles and books published on this topic in the National Archives.

Jan 2000–Mar 2002  

Research: Idiopathic Epilepsy (Idiopathic Complex Partial Seizures)-A Culturally-Bound Syndrome?

Portland State University · Community Health · Portland State University

Portland, OR

Medical Anthropology, Complex Partial Seizures, Psychosomatic disease and medicine; mindbody healing. Culturally-bound syndromes (i.e. Inuit pibloktoq and Native American preshamanism) were compared with western medical teachings on epilepsy and other recurrent seizure syndromes. Certain commonalities between the different syndromes across cultural boundaries suggest cultural behavior related to social, family, and professional medical and government input play large roles in determining long term outcomes for such conditions. This is evidenced by distinctive changes in incidence, mortality and long term outcome/recovery rates documented by WHO data, epsecially across US-Mexican borders and between certain neighboring African countries. Much of this evidence is related mostly to simple and complex partial epilepsy syndromes, and does not apply to seizures brought on by well document genetic and physical (injury or chemical based) causes. The most popular theory for behavioral change regarding disease history and diagnosis that can be related to this finding is the theory of learned helplessness published in many medical journals.

Jan 2000–Dec 2000  

Research: Cross-culturalism and Health: an important part of the Early American Experience

Portland State University · Community Health/Geography · Portland State University

Portland, OR/Denver, CO

We typically think of cross-culturalism during colonial times as the introduction of technology, new inventions and religious teachings in exchange for art, music and other unique parts of the Native American lifestyle. In fact, medical knowledge and discovery was exchanged in both directions, along with the beliefs in heath and healing methods typically practiced by each of these cultures. Unusual exchanges of information do exist in the historical documents but are rarely reviewed and covered as such by academicians. Some of the most important examples of these cross-cultural exchanges are reviewed, including the incorporation of children’s playing cards and other European products into an indian medicine bag, the sale of Iroquois baskets and sassafras at a 1647 Dutch farmer’s market in New York, the introduction (naturalization) of new medicinal plants to the New World as early as the fourteenth and fifteenth centuries by Viking explorers and missionaries, and the development of metis, French-Indian, French-Dutch, Christian-Indian, curee-shamanic, Creole, and other multicultural healing faiths during colonial and early post-colonial years. Similarly, disease migration patterns must be interpreted as two-directional events, with natural vectors and carriers residing at both ends. Examples include Measles and Small Pox, which were exchanged for intestinal tapeworms from Africa, Yellow Fever from the tropics, and Amoebic Dysentery from South America.

Jan 2000–Jun 2002  

Research: Oregon State Toxic Release Sites Mapping (GIS)

Portland State University · Community Health · Portland State University

Portland, OR

ArcView/ArcGIS-IDRISI32 GIS project. Developed spatial statistics formula from a combination of EPA, AMA, and NIH equations used to predict exposure severity and need for monitoring. Developed contour/isopleth modeling technique depicting potential exposure to individual chemicals, chemical groups, toxicity groups and SIC-defined chemical classes based on toxic release site chemical release data. Mapped more than 4000 standard EPA release sites reported since 1985, including 12 Superfund, 83 Superfund Applicants, 75 dumpsites, 7 watersheds, 24 mining/military test sites, 1 military chemical agents storage facility, 453 Confirmed release inventory sites (cris), 2273 toxic release inventory (tris), and 980 historical (cleaned) sites; database developed for 60K chemical reports, including chemical amounts and concentration information for 198 chemicals identified by EPA as important, their byproducts, and biological (microbial) end-products. Outcomes compared with CERCLIS data on US, by state; companies reviewed based on SIC data, site/corporate age and release amounts; SIC groups reclassified (merged) based on chemical types and groups, and levels above or below EPA standards; 6- to 15-bar histogram depictions were developed for each chemical class or group and applied to GIS, producing maps for 47 such “fingerprints” across the state; chemical fingerprints were then used to relate document chemical presence for site based on SIC-related histories and/or identify causative factors for local medical histories, and/or for prediction of chemistry of sites with known SIC history but no documented chemical testing history in the state or EPA database. DEM applications were then applied to one urban/suburban region.

Sep 1999–Dec 1999  

Research: Southeast Asian Population Health

Portland State University · Geography · Portland State University

Portland, OR

A review of the history of population health in this developing country, with emphasis on population census-related health information provided by WHO. The most important health issues were reviewed and the impact of post-war migration into the US on US population demographics and health status during the 1970s. Exercises on interpreting disease ecology, morbidity/mortality indices, and demographics were developed for use with highly popular World Geography undergraduate college textbook and related educational video/CD programs focused on Laotian-Hmong comparisons and the high birthrate for Hmong communities in Southeast Asian and the US.

Jul 1999–Apr 2005  

Research: The Ecology of West Nile (GIS)

Portland State University/Colorado State University · Community Health/Bioagricultural Science & Pest Management · Portland State University/Colorado State University

Portland, OR/Poughkeepsie, NY/Denver, CO

2000 – 2004 field research. Studied: Phytoecology of Culex vectors, Corvidae carriers, and livestock/human host species; species-phytochemical relationships (vegetation richness patterns in relation to species diversity); relationship of distance from water edge across a 5-mile flood plain to vector species types and diversity, species concentrations, and human susceptibility to west nile infection (transect analysis; penetrance); relationship of distance and elevation above local waterbody surfaces to species type/diversity and penetrance (transect analysis); relationship of NLCD to vector/host behavior; use of Landsat/AVHRR in determining terrain vegetation pattern relationships to disease patterns (field study); use of Aerial photography to define weighted centroid for species- and positive testing trap sites and identify best positive testing area; use of small area analysis to eliminate local species of hosts, vectors and carriers from cause for human infection with unknown source; swarm ecology and prediction using GIS in an urban setting; applications of these NY study outcomes to future Colorado pest ecology monitoring programs. Results presented at April 28, 2004 CSU presentation, and as part of ArcGIS/ArcView ESRI Health/GIS conference (Communications Award recipient, October 2006).

Jun 1999–Dec 1999  

Research: Overland Trail Demography

Portland State University · Geography · Portland State University

Portland, OR

Immigration records were kept at several locations on the overland trails, including several jump-off sites, government-operated forts, an Oregon toll station, and the site for obtaining land grants. Records were also kept of the arrival of settlers by several local newspapers and by government-requested local censuses produced throughout the late 1840s and early 1850s. This demographic information was reviewed in relation to Oregon Trail migration and medical history documents. Retrospective counts of the migration produced by immigrant families as part of their attempt to document trail migration history were also reviewed, along with data provided as part of the land grants records and late 19th/early 20th century genealogical histories. This research enabled important trail population conclusions to be drawn about family types and size, number of children per family and per team, and the morbidity/mortality conclusions that could be drawn from this information. Based on these conclusions, the most treacherous, dangerous and endemic/epidemic prone sites along the trail were identified. (For details, see Thesis appendix). Two disease areas were defined: an asiatic cholera region dependent on climatic, meteorologic, hydrologic, pedologic and human population features, and a dysentery region defined primarily by topographic and climatic features.

May 1999–Sep 1999  

Research: Hudson Valley Medicine: ca. 1500 to 1870

Portland State University · Chemistry/Geography · Portland State University

Portland, OR

Between 1500 and 1700, the Hudson valley tradition of living changed considerably from indigenous culture to an early Euro-american/indigenous culture. This multicultural history gave rise to numerous forms of medical care and practices, including adaptations of certain portions of traditional Native American philosophy and medicine and other colonial cultural beliefs into the most commonly accepted professional medical philosophies and regimens for the time. The Hudson Valley history of medicine is unique in that it includes both Dutch and English traditions, to which numerous other European traditions were added including Irish, French, Spanish, Portuguese, Moravian, Germanian, Scandinavian, African, and South American. In addition, the various forms of local Native American traditions of healing were vastly different across Iroquois Indian nation and local non-Iroquois tribal settings. This ethnic diversity gave rise even more diverse religious faiths for the region, including the first documented evidence for a Jewish physician practicing Ashkenazi and natural theological (pre-Hassidic) medicine in the New World ca. 1735. A collection of unique vade mecums, personal diaries and journals, recipe books, local newspapers and locally published medical books, local late 18th/early 19th C medical association meeting notes, and some of the first American medical trade journals in this country provide important insights into this aspect of regional colonial and post-colonial medical history, 1740-1820. This research analyzed the evolution and changes which took place during these early stages of development of American medical practice. Many of these changes are attributed to Dutch influence and the Dutch political and sociocultural support of multicultural living practices. These political and social setting made the Hudson Valley one of the most influential regions of the Colonial/early post-colonial medical practices, impacting medical tradition and philosophy in this New World for decades to come. A materia medica with notes on the philosophy of medicine during this time period was developed.

Jan 1999–Mar 1999  

Research: Hudson Valley (NY) Foodways (GIS)

Portland State University · Geography · Portland State University

Portland, OR

Hudson valley cultural history; fast food industry; pizza manufactories. Study included Native American and Dutch-English history of region; Hudson river ecology and agricultural influences on local foodways; synopsis of types of fast food/restaurant businesses per county, NYC to Canada; a review of the average price, per county and township, along the tourist route travelled from New York City to the Canadian border, based on simple fast food meal prices (<$3 NYC-Yorktown area to >$7 adjacent to Adirondacks Park). Statewide restaurant information was categorized by ethnic type (Italian, Mexican, African, Cuban, Oriental, etc.), average cost per plate, and annual income, and related to local census, local income data; results mapped by county; low income/SES regions related to tourist routes and tourism costs.

Jan 1999–May 1999  

Research: Development of an Algorithm for explaining and predicting local elevation/watershed-linked disease patterns

Portland State University · Geography · Portland State University

Denver

Developed equation used to predict high risk areas relative to elevation above closest water surface, applied across an ever-changing topography and surface elevation measurement. Equation is based on waterborne disease- or toxin-spread behavioral patterns and may be applied to all but one stream classification type based on local physiography. Ras-Vec/Vec-Ras conversion process for DEM/grid/ras files developed, followed by application of two equations which define routing patterns based on quad and cubic trend analyses. A 3D surface model was developed demonstrating impacts of topography, peririparian surface features, and elevation above sea level 2D surface slope features on direction of migration of waterborne disease agents or toxins. Elevation accounted for 75% to 88% of disease behaviors, whereas surface topography accounted for just 12% to 25% of the disease migration behavior. High risk areas for potential toxin/disease spread were identified using this model.

Jan 1999–Dec 1999  

Research: The Utilization of Herbal Medicine and Nutritional Supplements by Athletes

Portland State University · School of Community Health · Portland State University

Portland, OR

The herbal medicine/nutritional supplement marketplace was reviewed and types of products developed and ingredients used databased for analysis of recipe content and absence/presence of scientific and non-scientific validation of labelling claims. A number of products were found to have allied health sciences-backed claims and potential validity, with most products bearing based based more on scientific pharmaconutrient theory and speculation at the professional and paraprofessional level. Products with highly supported claims bearing medical and pharmacological support were rare. The most common claim: utilization of steroidal substitutes (esp. pre-human steroid, steroidal alcohols) for purported human steroid effects. The most common unsupported claim: the use of diuretics in weight loss management. The most reputable claims: utilization of certain stimulants with founded pharmaceutical effects (ephedra, yohimbine, and caffeinics), and certain nutrients with purported nutriceutical effects such as L-carnitine, Coenzyme Q, and certain amino acids.

Jan 1999–Dec 2000  

Research: Oregon Lyme Disease Ecology (GIS)

Portland State University · Community Health/Public Health · Portland State University

Portland, OR

Key Words: GIS, Borrelia, Ixodes, Chrysotile. The ecology of Borellia was reviewed in relation to local rodentia habitats and ecology. The most common vector, Ixodes, was reviewed in relation to the various natural setting of the states of Oregon, Washington and California. Population, land use, human occupational and recreational land use habits, and physiographic features were mapped in relation to disease behaviors in the state and nearby states, defining a well-defined natural boundary for lyme disease diffusion based on one or more spatial features. The most likely physical feature responsible for preventing intrusion of Ixodes into southwest Oregon was determined to be related to the Chrysotilic formations. Features possible preventing disease diffusion across these regions include lizard population history (has a natural anti-borrelia agent), plant history (lack of rodent-feed suppresses vector behaviors), and some undefined water-geologic-soil chemistry relationship with Ixodes and/or borrelia.

Sep 1998–Dec 1998  

Research: Circumpolar Native American cultures: Inuit identity and Nunavut (GIS)

Portland State University · Geography · Portland State University

Portland, OR

The circumpolar region of the earth is a distinct geographic region, with its own unique climate-based cultural behaviors and socioeconomic cultural survival activities. This work included a review of the history of Inuit (Eskimo) culture in the US and Canada, and a comparison of Inuits with other circumpolar groups in Russian and Northern Europe. The impact of foodways and history on the development of Nunavut’s borders were reviewed, with boundary selections shown to be based primarily on the ecology and spatial distribution of locally harvested natural resources (esp. Ceta and Bos ecology). Data from maps of Nunavut were entered into GIS and used for presentations and analysis of Nunavut politics in relation to biodiversity and natural resource availability.

May 1998–Sep 1998  

Research: The Spatial Distribution of Indigent/Homeless Population Sites (GIS)

Portland State University · Geography · Portland State University

Portland, OR

Three requirements for camping areas were identified: proximity to major roadway used for in-migration/out-migration of urban setting, presence of well-protected natural settings urban center and borderlands usually involving parks, establishment of multiple, active community-based support programs (primarily government services, health/mental health treatment, and food providers) located in close proximity to encampment areas. Unreported, underreported and misreported population census counts were identified.

Jan 1998–Apr 1998  

Research: Predictiing Biological Soil Content using Proximal and Remote Sensing (GIS/RS)

Portland State University · Geography · Portland State University

Portland, OR

A narrow multiband (2 nm) soil proximal sensing sensor was used to document surface soil features for Antarctic periglacial exposed soils. Two periglacial, peririparian soils were compared and found to contain distinctly different wavelength readings across several portions fo the bands. Excluding the impacts of mineral/rock type, it was found that three specific peaks could be isolated and reviewed (430, 520 and 540 nm). These peaks were found to be related to algal photochemical conent, in particular the presence of xanthophylls and chlorophylls. The possible impact of proanthocyanogenic was also reviewed. In the infrared range, overall distribution of peaks was significantly greater and more complex for soils demonstrating possible photochemical content. In sum, even though the two antarctic steams upon first glance and subsequent macroscopic testing appeared quite similar, proximal testing of soil reflectivity demonstrated distinct differences in these two soils, possible due to algal disintegration and implied water or peririparian algal blooms in nearby river or soil features.

Jan 1998–Apr 1998  

Research: Impacts of Plant Structure and Composition on Remote Sensing (GIS/RS)

Portland State University · Geography · Portland State University

Portland, OR

IDRISI project. Study of relationships between cytochemical architecture, phytochemical reactivity, and reflection-absorption features of surface features on Landsat MSS, TM and LS8 remotely sensed images. Reviewed the impact of common and stress-induced photochemicals, near UV- and Vis light reactive alkaloids, tannins and other chemicals or pigments, metal ion and starch granule content, water content, stress-induced changes in surface chemical (reflective cerum/wax) and pilar features, and crystalline-like patterns produced by specific cellular organelles.

Jan 1998–May 1998  

Research: Phytochemica (GIS/RS)

Portland State University · Chemistry/Geography · Portland State University

Portland, OR

Phytogeography, metabolic pathways, primary and secondary metabolites. Produced folio depicting major chemicals pathways for primary and secondary (tertiary) metabolic products; related to Remote Sensing/GIS documentation of stress-induced RS (AVHRR) changes in phytogeography and reflection patterns detected for plant/algae-rich soil. Based on study of Antarctic soil RS patterns and reviews of changes in water and chemical (especially photochemical) content of highly stressed plants, and changes in surface patterns and structures. Subcellular changes in cytoarchitecture and tissue-related chemical features explored for AVHRR impact.

Sep 1997–Dec 1999  

Research: Disease Diffusion Modeling (GIS)

Portland State University · Geography · Portland State University

Portland, OR

Gerald Pyle’s Disease Diffusion Model (first published description, 1967) defines the disease propagation process as a result of human population and transportation features. This model relies primarily on public transportation methods to facilitate the spread of contagion, and human population density as the means to define places where the disease is most likely going to reinitiate an epidemic or spread of disease to new victims. A number of modifications to this pattern may be made based upon documented epidemiological behavior patterns dependent of other factors beside simple human population density. A review of Asiatic Cholera epidemiological patterns demonstrated that population density, although it plays an important role in the propagation process, is not the primary reason this epidemic spread the way it did throughout the 19th century. Whereas transportation routes and heavily populated areas played important roles in determining where this epidemic erupted, once a small scale area analysis was performed, it was demonstrated that this disease typically did not initiate in the most densely populated regions. In fact, a reversed hierarchical diffusion process prevails worldwide for asiatic cholera, when we define this hierarchy based on population density features in combination with socioeconomic status. As documented in hundreds of articles published in the medical journals, certain subpopulation groups were mostly likely to catch the disease throughout the nineteenth and early twentieth centuries. Their infection by vibrio facilitated its dispersal throughout the remaining urban areas, including populations previously thought to be “immune” to cholera or exempt from becoming infected. The most important part of this reversed hierarchical feature in urban settings is the absence or presence of low income communities. This was demonstrated by the formation of disease niduses in low income communities, regardless of ethnic background. The primary factors responsible for this spread of cholera were identified as undernourishment, tight living quarters, poor water supply, unhealthy toilet/outhouse habits, unsanitary living and waste disposal conditions, and improper or non-sanitative medical treatment and disease prevention practices. This study updates Pyle’s cholera maps to present a more accurate depiction of cholera diffusion across middle and north American regions, differentiating cholera onset brought on by natural ecological means (waterborne disease onsets) from epidemics due primarily to human-to-human contact (human population diffusion methods of spread).

Sep 1997–Aug 2000  

Research: Oregon/Overland Trail Medical Geography (GIS)

Portland State University · Geography · Portland State University

Portland, OR

Health Geography, Disease Ecology, Spatial Epidemiology. Reviewed and identified all possible causes for numerous “cholera” epidemics along the overland trails, 1842 to 1853, ranging from mineral water- and food-induced cases, to giardia, listeria, cryptococcus, potentially cholerotoxic E. coli, and carcass-derived salmonella-intermedia induced opportunistic dysentery cases; mapped Mountain Fever (Rocky Mtn tick-fever) distribution, and local weather and other environmental features relative to elevation. With few exceptions due to population density features, vibrio cholera, amoebic dysentery and shigellic dysentery were ruled out. A new east-west route for Cholera diffusion not previously mapped by 19th century epidemiologists or medical geographer Gerald Pyle (1979) was discovered through the study of shipping documents and local newspapers in and around the US-Mexico border.

Sep 1997–Mar 1998  

Research: A GIS Application for Monitoring Mushroom Harvesting by Wildcrafters (GIS)

Portland State University · Geography · Portland State University

Portland, OR

GIS developed for monitoring mushroom ecology and impacts of harvesting by local wildcrafters. Economically, the most important genera were (one or more species of): Cantharellus (Chantrelle), Laetiporus (Sulfur Polypore), Pleurotus (Oyster MR), Boletus (Bolete), Hericeum (bears Tooth), Morchella (Morel), and Clavaria and allies (Club Fungi). Most important medical species: Ganoderma oregonense (Oriental and local Naturopathic medicine use). Most endangered species based on habitat, ecology and marketplace activity: Boletus smithii and possibly Hericium abietis, H. coralloides and H. erinaceus. Risks of overharvesting Oregon white truffles (Tuber oregonense and T. gibbosum), Oregon brown truffles (Leucangium brunneum), and Oregon black truffles (Leucangium carthusianum) remain uncertain.

Jun 1997–Oct 1997  

Research: The Diffusion of Eclectic Medicine, 1832 to 1875 (GIS)

Portland State University · Geography · Portland State University

Portland, OR

Enrollments in an Ohio school of Eclectic Medicine (neothomsonian, non-traditional thomsonianism) as published in the National Eclectic Medical Journal were reviewed, demonstrating typical hierarchical diffusion patterns defined by overland and river-based transportation routes during the mid-nineteenth century. Establishment of stable medical schools required location of eclectic schools in large satellite communities situated adjacent to allopathic schools with long academic histories. The political and legal history of this school in relationship to contemporary church-based hospitals and regular medical schools was also reviewed.

May 1997–Dec 1997  

Research: Michoacan 1976-1993 MSS and LS Imagery (GIS/RS)

Portland State University · Geography · Portland State University

Portland, OR

4 Satellite Imaging areas, 40+ images, 4, 5 and 6 bands each. Areas covered ranged from the shoreline of western Mexico, inland, to Michoacan forestry service area. All images were loaded into IDRISI and IDRISI32 programs, corrected, and merged, for evaluation of changes in landuse history. Focus of project was deforestation patterns related to indigenous forestry company-related activities. Additional work included the development and testing of an algorithm used to define partial roadway/transportation routes based on partial roads representation (based on formula published in IEEE/ISPRS annaul meeting transactions); development of methods to monitor changes in lake surface temperatures and surface algal bloom behaviors over time, brought on by industrial waste release; development of temperature ocean-surface monitoring formulas and techniques for use in defining el nino/la nina-related ocean flow/upwelling pattern behaviors and changes; applications of standard NDVI formulas for use in relating Mexico Vegetation Maps to image patterns; development of edge detector (3 x 15 filter pass) formula for use in enhancing stream edges in 3D surface models and SLAR images.

May 1997–Jun 1997  

Research: The Economic and Cultural Geography of Sassafras

Portland State University · Geography · Portland State University

Portland, OR

The ethnobotanical history of Sassafras albidum of North and Middle America was reviewed. The economic history of this important New World medicine has long been forgotten since the reduction in popularity of herbal medicines during the mid- to late twentieth century. The history of this important plant medicine was reviewed as an important piece of Native American history, followed by studies of the impact of sassafras as a newly discovered medicine on both European and Euro-american medical and pharmacal histories. By the turn of the seventeenth century, the journals, diaries and recounts of travellers and explorers indicate that since the discovery of sassafras and its documentation during the 1590s by Nicolas Monardes due to his expedition into Middle and South America, sassafras became a highly valued panacea in European culture. Its popularization by English royalty matriarchs during the late 1590s led to its popularization as a remedy for syphilis, resulting in the development of a highly productive drug industry in which Sassafras was gathered and sold in throughout the European marketplaces as the cure for syphilis. This popularization led to the development of an industry in which explorers searched for alternative sources for this medicine along the southern North American coast and into New England, due primarily to the monopolization of this market by the developers of New Spain, its primary source. During the next century, this popularity somewhat diminished, subsequent decades, but Sassafras nevertheless remained a highly popular New World herbal medicine to local marketplaces. With time, its use as a treatment for syphilis changed, as it became more popular and highly marketable as a blood tonic. This latter use for Sassafras remained the reason for its success throughout the nineteenth century., and the reason for its replacement by other more manageable herbal industries with similar tonic effects and tastes throughout the next century (i.e. birch and root beer sodas). By the twentieth century, its value as a flavorant remained an important part of non-allopathic pharmacopoieas and fodd industry uses for this botanical. By the 1960s, its popularity was diminished by findings of a possible link between safrole, its primary phenolic flavorant, and the possible development of liver cancer in rats test for exposure-carcinogenesis risk. The use of sassafras as an herbal remedy has since remained mostly a small scale cottage industry, and for the most part is excluded from any large scale herbal medicine industries due to FDA-related regulations.

Apr 1997–Jun 1997  

Research: Surface Edge Profiling Algorithm

Portland State University · Geography/Earth Sciences/Geology · Portland State University

Portland, Oregon

Remote Sensing, DEM, elevation change modeling algorithm. Developed formulas for comparing surfaces and for depicting major changes at the local level regarding slope/elevation above closest land surface objects (water bodies). Algorithm defines areas of high risk based on very local slope differences.

Jan 1997–Jul 1997

  

Research: “New World Syndrome” and Epidemiological Transition

Portland State University · Geography · Portland State University

Portland, OR

Diabetes, gall bladder disease, cardiovascular disease and metabolic syndrome longevity trait alpha-hypolipoproteinemia/beta-hyperlipoproteinemia partial lamarckianism

Jan 1997–May 1997  

Research: The Geography of Wildfires

Portland State University · Geography · Portland State University

Portland, OR

An investigation of the history of massive widlfires in Tillamook, Oregon, 1915 to 1950. This landscape was compared with those for other massive wildfires areas documented in the Eastern and Central United States, Europe, Asia, Central and South America, and Australia. Specific climate and weather patterns and surface geomorphology/biogeography features were identified as high risk factors for the development of the most destructive wildfires. Methods for monitoring and remotely sensing these features were discussed.

Jan 1997–Apr 1998  

Research: Asiatic cholera interpreted during the 1800s as an environmentally-induced disease

Portland State University · Geography · Portland State University

Portland, OR

More than 1000 articles pertaining to Asiatic cholera published between 1815 and 1865 were reviewed and catalogued for environmentally-related causative factors cited by the authors. These causes were classified and analyzed to determine the complexity with which human and natural environmental causes were cited. Such causes included special zooa- and non-zooa-related research topics including mammal and pest (early vector/carrier) ecology, weather and climate, solar activity, topography, land elevation above local water surfaces, slope and aspect conditions, vegetation features, hydroecologic setting (marsh, peri-lacustrine, per-riparian, etc.), soil type and chemistry, geology (calcium and non-calcium rich landforms), subterranean hydrochemistry, the absence/presence of local gas/air-forming waterbodies, formations, and soils, and local alkaline/saline water geography. The earliest American John Snow-like published medical geographers of the century were identified. The first description of a disease/cholera “nidus” (disease nest or birthplace) published in a medical journal was identified.

Jan 1997–Dec 1997  

Research: The Pharmacoeconomics of Medicines by Disease Groups/Subtypes

Portland State University · Chemistry · Portland State University

Portland, OR

Analysis of 1986 prescription and non-prescription drug utilization, per drug class/orgran system treated, including numbers of scripts, costs, etc. Analysis of 1996 OTC and prescription drug use by similar classes, including addition of cosmetic products, evaluated per container or product, per shipping unit, and per unit dose cost to consumer and market distributors. Highest cost product lines, system-related medical state(s), and drug companies identified.

Jan 1997–Apr 1997  

Research: Monitoring airborne plume waste dispersal from two major chemical manufactories (GIS)

Portland State University · Geography · Portland State University

Portland, OR/Vancouver, WA

A local paper manufacturer and aluminum products manufacturer were historically documented as high-volume toxic waste and plumage producers. These two sites were then monitored for their individual as well as combined effects on the local environment. A method was developed for the implementation of a geographic information system to relate waste production and dispersal patterns to types of human, wildlife and natural resource (soil/water) exposure that might ensue. Monitoring sites were selected based on GIS-related ecological, vegetation canopy, topography, landuse, population density, seasonal and daily wind patterns, and openspace features. Plumage dispersal was noted to converge over several protected wetland and wildlife habitat areas.

Sep 1996–Mar 1997  

Research: John C. Fremont’s Travels and Medical Topography/Climatology (GIS)

Portland State University · Geography · Portland State University

Portland, OR

Travel information: 1842,1843 (excluding winter months), Missouri to Oregon/California. More than 500 observation locations and encampment sites were identified based on diary entries. Barometric pressure, precipitation, temperate, and elevation data obtained from Fremont’s 2 volume 1850 diary publication was related to USGS Map data published around 1990. Data was entered in GIS and used to produce a map of Fremont’s expedition and a surface model of temperature/climate changes along the overland routes taken. This was then related to Asiatic cholera ecologic history, demonstrating the presence of a natural barrier to disease diffusion across the Rocky Mountains during the early and Mid-19th century.

Jul 1996–Oct 2000  

Research: The effects of population density of vibrio diffusion during the 1860s epidemics in the Netherlands (GIS)

Portland State University · Geography · Portland State University

Portland, OR

The diffusion of Asiatic cholera in the Netherlands induring the 1860s represents one of the only epidemics monitored spatially for which elevation plays a minimal role in the overall local diffusion process. Morbidity/mortality data provided by medical journal articles published at this time were related to GIS basemaps in order to demonstrate the pivotal role population density in large urban areas play on this disease diffusion process. Due to canal-related shipping routes, the influx of Asiatic cholera victims at this time resulted in a traditional disease diffusion process controlled largely by population size and density. Socioeconomic impacts were minimally represented in this study due to poor income-related data.

Jan 1996–Sep 1996  

Research: The Geography of 19th Century Complementary/Alternative Medicine

Portland State University · Chemistry · Portland State University

Portland, OR

Eclectic, Homeopathic, Physiomedical, Botanic, Thomsonian and Church-based medical school information and journals were evaluated at a local library (ca. 1790-1880 publications). Nearly all of these journals list the medical schools then active within their profession. Twice a year, these journals published the list of graduates from these institutions and often included their town and state of origin. This data was gathered and then evaluated for school distributions in relation to medical journals, on a per sect basis from 1800 to 1860. The diffusion of CAM influence was then evaluated demonstrating the expected hierarchical diffusion patterns. Religious backgrounds for some areas influenced the teachings of a number of these institutions. A number of urban settings were found to demonstrate nearest neighbor political effects within the medical profession, with one major town bearing regular medical schools and its twin urban location schools professed in one or more of the popular alternative medical practices then taught. Most of these urban settings established hospitals, which due to their primarily church- or religious group-sponsorsips, typically established clinical wards available to patients of all available medical sects for the time. The political history of this interdenominational clash for medicine was reviewed, uncovering several political tactics commonly employed by allopathy to improve their representation in this politically unstable profession.

Jan 1996–Jun 1997  

Research: The Rights of the Shaman

Portland State University · Chemistry/Geography · Portland State University

Portland, OR

The Rights of Native American/American Indian groups has long been a popular topic in the academic world. In recent years, this has once again become an important topic internationally due to the impacts of industrial nations on developing nations and their cultural settings. These changes have led to a number of UN gatherings, publications and social movements regarding indigenous intellectual property rights and indigenous cultural rights. This study is an overview of these social issues, with emphasis on several new concepts and legal rights being posed regarding indigenous rights. For the most part, these sets of rights tend to focus on: cultural and religious practice rights, integrative medicine rights, intellectual property rights (i.e. knowledge of botanical medicine uses), human genome rights (human genome project), and natural resource allocation rights (biodiversity and utility patent rights). Possible actions that may be taken by some of these ethnic groups are discussed, with example to past successful applications and recommendations for future applications with regard to natural resources utilization.

Oct 1995–Mar 1996  

Research: Interpretation of a late 19th C Iroquois Prayer Stick/Medicine Club

Portland State University · Chemistry · Portland State University

Portland, OR

A late 19th C Iroquois Prayer stick, yellowish to brown in color, made of a hard wood (maple? ironwood?), removed by artisan from a young 1″ diameter tree base; root crown consists of a 4″ spiney burl. Entire club is 17″ long, 4″ wide at burl, 1′ dia at base, with 5″ long area at end of shaft for holding this instrument during cermonial performances. Shaft contained numerous knots and bumps from carved off branches, and is fairly straight otherwise. Artist’s rendering on handle includes a carved and dyed map of a fairly straight stream flowing or river across a plains-like region, with spattering of dark brown resin/paint depicting bison, and red paint/resin-based colorant used to fill carved streambed. Icons adjacent to “stream” represent shamanic tipi (with small stream between this tipi and the remaining encampment), main encampment tipis surrounded by oval wall or barrier, south of stream bank is entrance to fortressed encampment, guarded by 2 animals (possible beaver). The river (flowing left to right toward burl) is painted (resined) red and dark purple, suggestive of Red River reservation(?). Other lines (paths) lead (leftward) to burl end, suggestive of foothills or mountain range. Burl has five major root bases that are carved into raven bills and faces. Lines/paths from the encampment lead to sections between these crowbills, progressing further (up into the hills for ceremonial purpose?) and finally toward the tips; these resemble paths going up the base of a series of mountains; scene resembles map of river heading westward, possibly across the northern Great Plains, along which bison survived and migrated into and out of the mountains. Another angled face of the shaft, just below edge of burl (to upper left of camp drawing) contains 4 icons symbolizing (in sequence, away from burl, high to low) sun-moon, prayer stick in hand with arrows (<<>>; depicting conversation to and from prayer stick), man&woman couple, four-spoke medicine wheel (bottommost iconograph). A fifth icon is placed at other end of shaft (5″ from end, just above handle portion, far lower left portion of stick); it consists of a prayer stick in hand and arm (lower and partial upper), to left are ‘<<<‘ arrows (carved in wood) radiating towards earth (“earth” symbolized by 3 squiggly dark blue lines/carved); lateral lines/carved and dyed, appear symbolic of soil, appear below the water lines and are of multiple colors (symbol for harvesting/ecologic prayer made to earth/environment).

Sep 1994–Aug 1996  

Research: Missionary Medicine

Portland State University · Chemistry/Geography · Portland State University

Portland, OR

The history of new World and US Christian missions and missionology. Reviewed cultural and ethnic interpretations of health and disease, relating philosophy to medical practices engaged in and interpretations of natural events, including illness. Sects reviewed include late 16th C. Roman Catholic Canades/New France missions, 16th and 17th C Micmac missions, 18th and 19th C. Colonial North American Moravian missions, 19th C. Hudsons bay company-related US-Canadian Missions, 19th C. Midwestern missions, 19th C. Pacific Northwest and Vancouver-Canada missions. Materia medica, foodways, healing faiths, individual and public health practices, religious influences on healing practices, shamanic beliefs, and domestic health culture reviewed and catalogued. The most important outcome of this lengthy review was the relationships drawn between traditional missionary medical practices and beliefs and the earlier practices noted in the New France writings: the concepts of sanative healing promoted by the late 16th C. Nun’s hospital in Canada (New France) and subsequent practices of the same by missionaries enabled links to be established between Native American and European religious philosophy, to such an extent that the progress of certain missions could be better understood. Those most effective at producing Christian Indians during the later colonial years (18th C), i.e. the Moravian Mohegan Missions in Pennsylvania and New York, are the best demonstration of this historical cross-cultural impact.

Aug 1994–May 1995  

Research: Distribution Patterns of Great Plains Flora along the Overland Trails

Portland State University · Chemistry/Geography · Portland State University

Portland, OR/Grand Island, NE

Evidence for the environmental impact of the overland migrations of ca. 1845 to 1860 are readily noticed due to distinct vegetation patterns noted in studies of the Great Plains. These distribution patterns were related to ethnobotanic and ecologic history. Several unique human ecology features were uncovered due to impact of human migration across this region. Certain Polygonum spp. esp. P. persicaria, distributed in very close proximity to the trail in spite of significant climate and weather patterns changes across these states, remain in these locations due to the long term impact of human migration on local ecology. A Cleome sp. found to demonstrate diffusion eastward, suggesting its passage back to populated regions in Missouri may be due to its popularity as a herb of medicinal value following its mid-19th C discovery and publication in the medical literature. More recent impacts were noted by the presence of other species in the wild which are typically bound to urban settings, such as the introduced Aesculus spp. and Ailanthus glandulosum; these demonstrate a classic radial diffusion pattern around the most heaviliy populated urban settings. Due to Russian in-migration in the middle 19th C, accidental seed and domesticed food crops were introduced along the Mississippi and Missouri rivers, including Chenopodium and other Caryophyllidae tumbleweeds; these demonstrated three locations for introduction to the Great Plain, primarily at its northern end. A Platte River Rumex species was often mistaken in historical writings as an Armoracia; the harvesting of a Euphorb species (Croton) was often mistakenly interpreted as a food-related note rather than a medicine. Finally, the distribution of a Eupatorium species was found to be linked to the large number of infant deaths noted in western Nebraska due to accidental milk poisoning. All distributions of ethnohistorical importance were mapped and databased.

Mar 1994–Sep 1995  

Research: Tuality Hospital/Southeast 8th Avenue Trimet Lightrail station

OTAK, Inc. · Architectural Services/Urban Design

United States · Portland/Tuality, OR

Environmental Engineering

Sep 1993–Sep 2010  

Research: Epilepsy, Creativity and Genius

Portland State University · Chemistry/Geography · Portland State University

Portland, OR/Denver, CO

A metaanalysis of literature on creativity, genius and epilepsy. The relationship between epilepsy and creativity has long been a topic of argument in academia. The association between cases of epilepsy and IQ, academic performance, and various types of skills testing has for the most part been questionable at best. In general, a test of this association between a condition or illness such as epilepsy, and genius or creativity, is greatly hindered by its variety of physical and psychological causes, the numerous social networking models that can result from a seizure condition, the varied lifestyle-related issues people with epilepsy have to face, the range of personality profiles they can exhibit and the impact of combined genetic, physical, neurochemical and behavioral influences on each epilepsy case profile, are the primary reason a study of this type of syndrome or medical condition is questionable at best. Putting genetics and the physical attributes related to the seizure-related living condition aside, the behavioral, psychological, sociological and cultural aspects of the epilepsy lifestyle do have impacts on living and learning skills expressed by people with epilepsy. When people with epilepsy of just idiopathic or relatively undefineable or unknown cause are reviewed, results demonstrate stronger relationships between psychological and social behaviors of people with seizures, that in turn become more likely to impact life goals and long term personal choice-related outcomes. A common theory for creativity and genius defines a particular form of this expression as the result of overcoming personal limitations. Whether or not these limitations are the cause for this outcome, or are simply a means for the body to learn new skills and endurance steps to take in performing certain tasks, is uncertain. What we do know is that people with chronic life conditions like epilepsy, tuberculosis (common in 19th C), MS, ALS, psychiatric illness, and even sensory-impairment become well known once they are identified as creative high achievers. Illness or chronic condition has its own impacts on life changes and performance. Social interpretations of this part of life also has its impact on personal goals and achievements. With epilepsy and several other neurological/neurochemical-related medical states, it is possible there are normal activities within the central nervous system at play in producing the overachieving scientists or highly creative artists and writers. Their over-activity (a physiologic cause for this end state) in combination with the ability to focus this hyperactivity (the psychological, cognitive cause for this end state), may perhaps be the cause for creativity and productivity of people with seizures, MS, and other neurologic conditions. This relationship is more easily observed, studied and the results analyzed and criticized when people with idiopathic epilepsy are the focus of the study for seizure victims.

Sep 1993–Aug 1996  

Research: History of Naturopathy

Portland State University · Chemistry · Portland State University

Portland, OR

Oregon is one of 6 states in the US that allows for state certification of naturopathic physicians. This is due to the existence of one of two accredited schools of naturopathy in the United States (the other sschool is in Washington). This study begins with the history of the Oregon School since its birth in 1956. The history of its ND program and student-faculty populations were reviewed. The politics of non-allopathic schools locally is discussed, along with numerous political actions taken by the school of naturopathy to keep the profession afloat, such as the development of its Seatlle, WA branch in 1973, the co-sponsoring of its pre-med programs and required science curriculum by several midwestern colleges, the inclusion of Oriental medicine into its program in 1982, the development of a systems science approach to teaching in 1988, and the conversion of the Oriental College of Medicine to its own alternative medical school program by 1989. The history of naturopathy since the coining of this term as a medical profession in New York is covered. The separation of naturopathy from chiropractics in 1933, as taught by the Oregon School of Chiropractic Medicine is also discussed due to the underlying political turmoil which led to the establishment of naturopathy as its own unique profession with a distinct degree title (ND, no longer MD). This study includes a review of naturopathic professions by the State DA in Utah, 1956, in which a complete review of the history of the profession in the US is detailed, including reports of visits to all Naturopathic schools then active in the United States.

Oct 1992–Sep 1994  

Research: Pacific Rim Shipping Routes, 1845-1855 (GIS)

Portland State University · Chemistry · Portland State University

Shipping routes and port histories were defined based on lists of ships published weekly to biweekly in Sandwich Island, Panama, California, and Oregon newspapers published ca. 1845-1855. These routes depict the history of commerce along the pacific rim and demonstrate differences in speed, population and disease spread based on ship size and type and national origin. Used to define most likely ship-borne epidemic routes for disease during this time in west coast history for comaprison with overland routes.

Oct 1992–Oct 1999  

Research: William Dain: Thomsonian/Indian Medicine, Trapper and Overland Trail Physician, ca. 1820-1870

Portland State University · Chemistry · Portland State University

Portland, OR

Researched and developed materia medica for 1845 vade mecum, including use of Eastern Thomsonian/Eclectic, Great Plains, Rocky Mountain and Pacific Northwest herbal medicines. Trapper/Indian Medicine serving Fort Vancouver area at the Oregon-Washington Territory border, 1842-1870. Oregon Trail physician, 1845+. Popular alternative medicine herbalist-physician during Civil War and post-bellum years.

Oct 1992–Aug 1996  

Research: Intellectual Property Rights, Bioengineering and Ethnobotany

Portland State University · Chemistry/Geography · Portland State University

Portland, OR

Researched history and development of various intellectual property (IP) rights and Patent laws with applicability to the ethnobotany-bioengineering fields. Reviewed recent history of IP legality changes, indigenous knowledge and cultural property/knowledge rights, the early development in agricultural crop farming rights and crop bioengineering/gene patent rights, the establishment of seed, cutting and cloned property rights, and the establishment of the utility patent. Applied potential applications of these laws to numerous pharmacobotanical products.

Aug 1992–Aug 1994  

Research: Unaniism: A new pop culture healing faith in the United States

Portland State University · Chemistry · Portland State University

Portland, OR

The history and roots of Unaniism (unani-tibb) of Iran/Iraq. Its philosophical roots in the hippocratic faith, with Islamic additions and a unique take on Hahnemannist homeopathic philosophy through the development of unani methods for treating psychologic problems. Signs of emergence as a popular culture in alternative or complementary medicine and as an adjunct to sufi activities and lifestyle. A review of Hamdardism and Hamdard professional publications.

Jun 1992–Sep 1993  

Research: Klamath Indian Ethnobotany

Portland State University/Reed College · Chemistry/Anthropology · Portland State University/Reed College

Portland, OR/Klamath, OR

A Klamath Indian site was surveyed for vegetation types and ecology. Ethnobotanical remains were identified at the site absed on a map developed during the 1970s. Plant remains were reviewed and identified, and compared with site ecology. The most important plants for the immediate location were identified, with emphasis on unusual, culture-specific ethnobotanical identifications.

Jun 1992–Aug 1995  

Research: Dr. John Kennedy Bristow (1814-1883)’s vade mecum and Biography.

Portland State University · Chemistry · Portland State University

Portland, OR

A Thomsonian-Eclectic-Physiomedical medicine study. History of Complementary/Alternative Medicine. 150 pp vade mecum (recipe book) transcription and materia medica review. Other biography-related topics reviewed: physician’s family history and biography; educational/mentoring/apprenticeship training history; Great Plains and 1849-1852 Oregon Trail medical history; Oregon state complementary medical history; regional epidemiological history; professional unions/AMA and NEMA history; Oregon state medical boards history.

May 1992–Aug 2010  

Research: A bibliography and historical review of medical geography publications prior to 1870

Portland State University · Geography/Community Health · Portland State University

Portland, OR

The 1865 to 1899 index-catalogue series (ca. 80 vols) was reviewed for all known and identifiable medical topography, medical geography, disease ecology, and climate/weather-, soil-, geology-, montane-, lacustrine/riparian-, hydrology-, and natural disaster-related topics. Topics and knowledge diffusion reviewed by nationality, dates of journal/book publication, and key early medical geography/spatial epidemiology author names. The earliest publications of disease and medical maps by various medical journals were reviewed; the most historically important early western European demographers and biostatisticians were identified; cross-cultural influences analyzed; the most important influences of Soviet Union and eastern European countries on contemporary spatial epidemiology were documented.

Apr 1992–Sep 1993  

Research: Water Cure on the Oregon Trail, 1849-1857

Portland State University · Chemistry/Geography · Portland State University

Portland, OR

The first graduates of early hydropathy schools in the US made their way to the Oregon Trail as early as 1849 according to reviews of trail diaries and research published by trail diary experts. This review of several Oregon Trail women trained in hydropathy related their knowledge and experiences with those of Oregon Trail physicians. Unlike traditional doctors, Oregon Trail hydropaths were experts in documenting trail climate, weather patterns, water conditions, livestock fatalities, and overall family health status. By concentrating on good nutrition and healthy living, in particular the practice of sanitary cooking and water use conditions, many were able to avoid fatalities experienced by other wagons.

Nov 1991–Jun 1992  

Research: TLC project: Protoberberine alkaloid, Carotenoid and Flavonoid Content in OTC Spices and Herbal Medicine Formulas

Portland State University · Chemistry · Portland State University

Portland, OR

Food/Nutritional Supplement Chemistry. Thin layer chromatography used to compare carotenoid and flavonoid content of OTC products containing similar herbal/algal ingredients, and hydrastine-hydrstinine content of OTC Hydrastis (Goldenseal) products. Included analyses and comparisons of protoberberine alkaloid product, carotenoid, xanthophyll, and flavonoid content for similar products; related product chemical content in relation to label claims; documented degrees of product-related adulteration and substitution, documented reduction in product longevity/shelflife due to product preparation, storage, and containment techniques. Documented extremely-limited shelflife of powdered hydrastis products due to 3-month oxidation of hydrastine and reduction in shellife/hydrastine halflife in relation to storage temperature, humidity and other environmental features.

Sep 1991–Sep 1992  

Research: The Materia Medica and Philosophy of New France and New France Indians

Portland State University · Chemistry · Portland State University

Portland, OR

Published in a late 19th Century 71 volume series on New France papers 9facsimile rerpints), the philosophy of disease and medicine, use of medical devices, practice of European and Native healing, and selection of materia medica were documented. Several dozen allied documents (dairies, journals and papers pertaining to French travellers and explorers and the Hudson Bay Fur Company) were also documented. Results of study databased and published as a 1000+ page document.

Sep 1991–Dec 1992  

Research: The Trappers’ Materia Medica

Portland State University · Chemistry · Portland State University

Portland, OR

More than 300 original journals (ca. 1750-1880), journal reprints, letters, company papers, pocket books, and other incunabula penned by trappers, trapping companies and trapper-related explorers were reviewed and then databased. A description of the medicine or medical instrument/object, its identification (esp. latin name) and analysis and a commentary on the philosophy regarding its use, were produced and summarized into a 500+ page document.

Jul 1991–Dec 1992  

Research: Triomancy in Early 19th Century New York Medicine

Portland State University · Chemistry/Geography · Portland State University

Portland, OR

Between 1790 and 1800, the yellow fever epidemics striking New York City and parts of the Hudson north of the city were intrepreted as theological events, initiated by the wraths of God and the like. Even the most non-Christian settlers came to interpret this recurring epidemic as a sign of poor living habits and and inappropriate human behavior. A review of early sermons publisehd during this time in the New York and lower New England area contained undeniable testimonials, influential not only on churchgoers, but also their neighbors not active in the traditional church setting. Over the next few years, yellow fever became known as the triennial or three-year fever. By 1849, this term was linked to yellow fever as far away as Louisiana. Both triophilics and triomancers came to respect the yellow fever as a sign of dissatisfaction expressed by the powers above. Since its cause was not known (and would not be known for another century), this theory for yellow fever continued to gain inpopularity and even gave rise to particular branches of healing faiths devoting to healing the triunal cause for this recurring epidemic disease and its deaths. The consequences of this unique socially-designed branch of medical philosophy and tradition had immediate and long term consequences, many of which became published confessions printed in medical books and journals. This study reviews the birth, rapid growth and maturation of trine-based medical theories, including many such theories still found in the professional literature today. Included in this review are examples of trine-based pharmaceutical recipes, techniques for performing complete medical care, and trine-based methods for healing patients common to 19th century allopathy and its alternatives,

Jan 1991–Apr 1991  

Research: Genetically engineered natural products from Oregon Forests

Portland State University · Chemistry · Portland State University

Portland, OR

The conversion of local forestry and horticulture-harvesting programs into bioengineering programs. Applications of plant tissue culturing callus methods for the development of such bioengineered products as: cascarosides, valepotriates, proteases, taxol, epipodophyllotoxin (Etoposide/TM), thalicarpine and thalictrine (cancer drugs); hederasaponins and Arceuthobium leaf wax (cosmetic applications); and larrea/xantholidic sesquiterpene-derived plant growth inhibitors/pesticides (agritech).

Jan 1991–Aug 1991  

Research: A chemical comparison of three Xanthoxylum herbal medicine products

Portland State University · Chemistry · Portland State University

Portland, OR

Xanthoxylum species are popular for their berberine-related alkaloids. Three species (2 American and 1 Chinese) are common to the US herbal medicine market. Their physicial state and chemical content were compared to determine whether or not they had similar chemistries, a most common requirement for shared medicinal use according to contemporary scientific thought. The Oriental species is sold in a moldy, fermented state, a requirement for its preparation for use as a Chinese medicine. This preparation greatly changed its underlying alkaloid chemistry, almost tripling the diversity of alkaloidal end- products and by-products. This also had the effect of broadening its potential physiological effects. The two American species demonstrated a simpler alkaloidal chemistry, and produced lower concentrations in extractions produced using the same test solvents for each series of speciments.

Sep 1990–Jun 1992  

Research: The Evolution of Plant Compounds: Fixed Oils as an Example

Portland State University · Chemistry · Portland State University

Portland, OR

Plant Seed Oils or Fixed Oils present a fairly easy-to-understand relationship between chemical type and diversity and phytoontogeny. Angiospermae in particular present a classic lignose to herbaceous conversion of fixed oils from C8 and C10 forms to moderately developed (and unbiquitous) C12 through C14 forms, to highly developed C16 to C22 forms. As part of this evolutionary process, we find the development of specific enzymes required to diversify oil chemistry, in particular the development of double bonds and even vinyl (triple bond), tricylic and pentacyclic containing oil products. The polyacyl/polyacetylene sysnthesis pathways and their end products are related to the placement of each oil class in an evolutionary tree. Medium chain oils are found to be most common in most plant subclasses, with short-chained fatty acids more common in tropically-developed orders/subclasses, and long-chain fatty acids with unique forms and unique end and side groups more likely to be found in highly diversified, highly evolved plant families, orders, and subclasses.

Aug 1990–Oct 1991  

Research: A Classification of Bitter Compounds in Plants

Portland State University · Chemistry · Portland State University

Portland, OR

Bitter-tasting plants are commonly used as phytomedicines. However, important chemical differences exist between these various plants due to the agents responsible for their bitterness. This review identified more than 25 distinct chemical classes responsible for the bitter flavor in plants, ranging from simple non-toxic complex tannins and iridoids, to selectively toxic phenolic derivatives such as quinine, to the highly toxic secologanin-Phenylalanine alkaloids and reversed triterpenes. This evolution of bitters as feeding deterrents in plants demonstrates several parallel pathways developed due to different chemical pathways. These developments took place at different times in plant evolution and diversification, with the earliest examples of pharmacologic complex pseudotannins by coniferae, filicidae and perhaps gnetae, complex tannins by hamamelidae, steroidal alcohols by filicidae, pharmacoactive biq bitters by archaic Magnoliidae et seq., reversed triterpenes by Dilleniidae-Rosidae base lignose populations, and bitter sesquiterpene lactone and iridoid derivatives by Asteridae.

Jun 1990–May 1991  

Research: Pigment/Carotenoid content of locally wildcrafted mushrooms

Portland State University · Chemistry · Portland State University

Portland, OR

Cortinarius spp. (esp. C. violaceus), Cantharellus spp. (esp. C. cibarius), Craterellus spp., Exidia glandulosa (Witches Butter), Lycoperdon spp., and Coprinus species were tested for stable coloring agents. Compounds extracted were compared with other known phytochemical pigments including complex tannins, flavonoids, iridoids and xanthophylls. With the exception of Cantharellus spp. (due to its complex carotenoid content=canthaxanthin) and Lycoperdons (black metal/tannin/iridoid-rich pigments in dry mature form), no pH/color-stable pigments could be identified.

May 1990–Aug 1992  

Research: The Ethnobotany of Sapota

Portland State University · Chemistry · Portland State University

Portland, OR

Key Words: Achras sapota, Latex chemistry, Rubber and rubber byproducts, biopolymer synthesis, bioengineering, Chewing Gum, Rubber, Aztec-Mayan ethnobotany, History of Mexico-Central American-Portland market (1840-1960), American Chicle Company. Thesis. Monograph.

Jan 1990–Aug 1997  

Research: Isaac Marks (c. 1725-1777), a Colonial New York Jewish Physician

Portland State University · Chemistry · Portland State University

Portland, OR/New York, NY

Dr. Marks practiced Medicine in colonial New York from 1730 to 1777. Most likely of London Ashkenazi Judaic descent, his practice included tradition Jewish health and disease prevention practices together with some of the earliest natural theologic teachings of Baum Shem Tov and local Dutch Boerhaavian medical traditions. Dr. Marks’s lifestyle constrasted greatly with the few dozen other Sephardic Jewish families in New York during this time, representing one of the earilest examples of Judaic medical practice engaged in as a part of New World colonial history. Much of Marks’s history is interpreted based on the writings of his apprentice Dr. Cornelius Osborn (1722-1783) and a small collection of financial and legal documents found in the local historical archives of the Dutchess County Historical Society.

Jan 1990–Dec 2010  

Research: Plantae: A Look at the Evolutionary Development of Chemicals in Plants

Portland State University · Chemistry · Portland State University

Portland, OR

A review of natural resource/economic botany utilization history by all stages in taxonomy, Division to subgenera/tribes), including summaries of ethnobotanic and pharmacologic findings and chemical relationships of plants in relation to this aspect of their natural history. Each Subclass section includes monographs on most important plants economically by Subclass (12 subclasses used), and special monographis on most unique ethnobotanical findings (immunogenic compounds, complex polysaccharide complexes (gum/mucilage evolution), latex development, seed oil classification and evolution, selective toxins, toxic syndromes in plants, anti-sickle cell meds, anti-leprosy compounds, semi-fossil resins, the Coriolis impact on isoprene chimer evolution, average annual/seasonal temperature effects on herbaceous resin/resinoid evolution, high T aviation LEAR seed oils/canola bioengineering, evolution of complex leaf cutin-wax matrices, symbiotic use of isoprenoids <20C, livestock toxins/teratogens, evolution of cancer drugs). End product: 600+ pp course text/textbook. Added materials include: Phytochemical chart (Plantae), Phytochemical evolution figures and biosysnthesis paths [includes photosynthetics (3 types), alkaloids (6 paths), tannins (two distinct paths), flavonoids (8 paths), phenolics/quinone, isoprenoids (<C30), sesquiterpene lactones, di-isoprenoids (C30 and above, steroidal, saponins, reversed triterpenes), N-C30s, lignans-lignins, neolignans, polyacetylenic/fatty acid evolution and production, etc.]. Also includes 80 family-order tables (row=genus) on plant chemical content and ethnobotanical notes (57+ cols); tables/figures/charts on statistical evaluation of chemical diversity of Genera by Family-Order-Superorder-Subclass-Class; statistical review of species/genus and family and related chemical diversity measure. Materials developed into a course text for 3-4 cr. Chemistry courses on Bioengineering of Plant Chemicals, Chemicals in Plants and Ethnopharmacology; in use, with annual updates, 1990 – 2000.

Sep 1989–Apr 1990  

Research: Glycyrrhetinic Acid content of locally marketed herbal medicines

Portland State University · Chemistry · Portland State University

Portland, OR

Several types of Licorice Root (Glycyrrhiza glabra) products were obtained from local herbal medicine marketplaces and tested for glycyrrhetinic acid content. This phytosteroid, common to the highly popular licorice root available in both American and Chinese medicine forms, exerts a mineralocorticoid effect on the human body, resulting in one or two Addison’s Syndrome-like cases reported each year to the local teaching hospital. Other endocrine-like effects were suspected as well, including glucocorticogenic, anti-glucocorticogenic, estrogenic, antiadrenergic, and anti-androgenic (anti-testosterone) effects. This resulted in the recommendation that warnings be required by all local herbal medicine packaging agents.

Aug 1989–Aug 1990  

Research: Local Herbal Medicines rich in hepatotoxic pyrrolizidine alkaloids

Portland State University · Chemistry · Portland State University

Portland, OR

Professional disputes regarding pyrrolizidine toxicity surfaced amongst local herbalists and licensed, accredited naturopathic physicians in Oregon beginning around 1989. This led to misrepresentation of the hepatotoxicity of “Coltsfoot” when one local herbal medicine specialist published a trade journal stating that western coltsfoot (Petasites sp.) lacked the hepatotoxicity associated with pyrrolizidine alkaloids. Traditionally, the eastern coltsfoot (Tussilago farfara), since it is in a distinct Asteraceae/Compositae subfamily or tribe, has been considered non-toxic or significantly less toxic than the western Petasites. In addition, past and present chemical research outcomes for these two species supports the claim that eastern Coltsfoot is less toxic than Western coltsfoot due to pyrollizidine content. Evidence also supports the conclusion that European tribes of herbal medicines related to Petasites demonstrate a significantly higher pyrrolizidine content and variety than North American garden and escaped varieties. Most important to this finding is the relative high hepatotoxicity associated with Comfrey (Symphytum) and other Boraginaceae herbal medicines due to similar alkaloid content. The most important herbal medicines in the Pacific Northwest regarding pyrollizidine intoxication are members of the Senecio genus, in particular the Mexican herb gordoloba (Senecio longilobus and close relatives). These species are contain cyclic pyrollizidines and Senecic acid derivatives known to be highly toxic. Several cases of intoxication due to misuse of this herbal medicine were recently noted in the medical literature and are expected to erupt locally as well in the future.

Aug 1989–Oct 1991  

Research: Portland Area Parks: Ethnobotanic Inventory and Plant Listings

Portland State University · Chemistry · Portland State University

Portland, OR

Developed natural plants lists for 7 of the largest, most frequently used parks, including Mt. Tabor (cindercone), Reed College Canyon/Crystal Springs park areas, Forest Park/Hoyt Arboretum area, and Forest Park/NW29th Avenue Trails to Audubon House area, Multnomah Falls recreation area, and Ross Island recreation area (Columbia river island habitats). Listing developed for identification of naturalized species with important local ethnobotany/natural resources histories. Utilized for outdoor presentations, 1989 to 1997.

Aug 1989–Sep 1991  

Research: The Toxicology of Herbal Medicines

Portland State University · Chemistry · Portland State University

AMTRA: Project IBIS · Portland, OR

Developed Toxic Syndrome (Toxidrome) database for inclusion in IBIS (CAM) diagnostic program and database produced by AVHRR. Produced descriptions and diagnostic profiles of ca. 50 classes of toxic syndromes (toxic plant chemical types) and profiles for 300 species-genus-specific toxic events; reviewed pregnancy-related complications of OTC nutritional supplements, reviewed phototoxicity/skin-sensitivity-related effects, provided descriptions of systems-related toxicity, abuse, misuse, and overdose patterns (including neuro-, nephro-, hepato, endocrino-, utero-, hemato-, immuno-, ophthalmo-, dermato-, musculo-, skeleto-, oro-, gastro-, tumoro-, and teratotoxicity effects).

Aug 1989–Oct 1992  

Research: Economic uses for members of the Plant and Algal Kingdoms, by Genus

Portland State University · Chemistry · Portland State University

Portland, OR

Key Words: Natural products, Phytochemical groups Plant Medicines, Toxicology and toxic syndromes, specific chemical types and names. Tabulated data for 12subclasses of plants and 8 algal kingdoms; for Plantae: approx. 250F, 25000 genera, ca. 150K spp., by K-C-subC-O-F-G, from species that are primarily gametophytes (moss, hepaticae, isoetes) to contemporary sporophytes (filicids, lycopods, etc. to gymnosperms, to angiosperms–monocots and dicots). 120 pp of tables (7.5 font, 37×2 cols.) were developed depicting uses for more than 150K species of plants. This is a GIS applicable dataset useful for phytoeconomic/agrieconomic/biotech studies

Aug 1989–Aug 1997  

Research: The Evolution and Economy of Cancer Drugs in Pacific Northwest Rainforest Plants

Portland State University · Chemistry · Portland State University

Portland, OR

Key Words; Taxol, Macrocyclic compounds Berberine alkaloids (homochelerythrine, sanguinarine), Naphthaphenanthradenes, Thalictrine/thalicarpine alkaloids, Neolignan derivatives (epipodophyllotoxin, Etoposide). Analyzed bark, stem, leaf, root content of ca. 20 local species, targeting content of above listed chemical groups and their derivatives. Employed TLC standard testing reagents and protocols to determine relative chemical make up, based on evaluation of water, alcohol, and water-alcohol-based extracts.

Jul 1989–Oct 1992  

Research: Northwest Natural Products Industries

Portland State University · Chemistry · Portland State University

Portland, OR

Developed list of important natural products in local rainforests and other fragile ecosystems not yet discovered, harvested, or documented for local industry use; design and development of related ethnobotany program with coresearchers; design of new methods for assessing and monitoring natural products harvesting and production. Results presented at a meeting in local capitol building, 1990/1, and as a part of various Oregon Academy of Sciences presentations, 1990-1997.

Jan 1989–Mar 1989  

Research: Tropical Rainforest Products

Portland State University · Chemistry · Portland State University

World Forestry Research Institute/Natural History Museum · Portland

Brazilian/Amazon Rain Forest Project Pacific Northwest Rainforest Project Ethnobotany

Aug 1988–Aug 2003  

Research: Secondary-tertiary Metabolite Production by Plants

Portland State University · Chemistry · Portland State University

Portland

Natural Products Ecochemistry

Aug 1988–Mar 1991  

Research: The History of Plant-derived medicines in Ophthalmology

Portland State University · Chemistry · Portland State University

Portland, OR

The history of ophthalmology, with focus on Middle Eastern, Arabian and Indian influences. Review of Al-Rhazes’ and allies’ formulas. Egyptian-Arabic folklore remedies. Unani remedies. The discovery of pilocarpine, eserine, papaverine, hydrastine, chelidonine, cocaine, physostigmine, belladonna alkaloids.

Jan 1988–Jun 1993  

Research: Benzylisoquinoline (BIQ) alkaloid synthesis pathways in plants

Portland State University · Chemistry · Portland State University

Portland

Natural Products Synthesis

Jan 1988–Aug 1996

  

Research: Secondary Metabolite synthesis in several Northwest Berberidaceae species

Portland State University · Chemistry · Portland State University

Portland, OR

Coumarins Tannins Alkaloids Achlys triphylla Vancouveria hexandra Berberis spp.

Oct 1987–Sep 2010  

Research: AMRTA/IBIS Program database development and updates

Alchemical Medicine Research and Teaching Association (AMR’TA ) · IBIS Program

United States · Portland, OR

CAM Pharmacology

Sep 1987–Aug 2002  

Research: Phytochemotaxonomy

Portland State University · Chemistry · Portland State University

Portland, OR

The Evolution of Plant Form and Chemistry in relation to Natural Products Development. Thorne’s and Dahlgren’s classification systems and several early alkaloid and flavonoid chemotaxonomic-derived systems were compared and merged to produce an evolutionary sequence more fitting of Farnsworth’s findings on metabolic pathways modeling. Basic mass-energy-time relationships were related to the evolutionary process and basic chemical diversification techniques utilized by plants. The Law of Mass Action was then applied to physical, strucutral and chemical features of plants, demonstrating that throughout the evolutionary process, plant physical make-up exists in balance with chemical make-up. Chemical evolution in plants follows three simple rules: 1) chemicals evolve from: simple to complex (simple monoterpene to iridoid), small to large (i.e. increasing lignin and cellulosic polymers, lignose to herbaceous sequence in evolution), one to many (ie. monomers to dimers/bis molecules, seed oil fatty acids, monoterpenes (C10) to diterpenes (C20)) or triterpenes/sterols (C30+), unbranched to branched (esterified seed oils), single to multiple bonds (i.e, saturated to unsaturated Dilleniidae C20s), one pathway to combined pathways (terpenoid-amino acid product mergers), 2) chemical changes towards increased chemical complexity usually take place at the expense of certain reductions in other recurring physical structural features, in this way energy for the production of one substance is diverted into pathways required for the production of another substance (for angiospermae, lignose and mildly toxic species, evolve into much smaller, non-lignose, highly toxic or selective species), and 3) chemical evolution takes place in such a way that later products are typically more selectively toxic and therefore more effective in evolution pathways and more useful as natural products/medicines. The most effective end-products are at the end of the evolution sequence in current time and/or exist in very old (evolutionarily speaking), well-developed plants that are still in existence.

Sep 1987–Aug 1988  

Research: Investigation of the alkaloidal halflife (potency shellife) of a popular herbal product: Goldenseal (Hydrastis canadensis)

Portland State University · Chemistry · Portland State University

Portland, OR

This popular, highcost herbal medicine is sold in numerous forms, ranging from tincture and fine powder forms to complete taproot (radix). Its most important constitutent, hydrastine, is a highly unstable benzylisoquinoline (biq) alkaloid due to a tertiary 5C-N ring formed over and sharing all but two elements with its three 6-member ring substructure. The loss of that ring results in the compound hydrastinine, a biq with different pharmacological attributes according to the contemporary Merck Index and Materia medicas. This greatly modifies the potential value of hydrastis products, in particular those in powder form. This study demonstrated an approximately 3-month halflife for hydrastis, resulting in UV SW-detectable hydrastinine detected using simple TLC techniques. Different hydrastis products were evaluated to determine logevity and potential value of hydrastis products based on drying technique, raw product storage, preparation, end-product storage, and other typical herbal medicine preparation and marketing processes.

Sep 1987–Apr 1988  

Research: Phytochemical Neurotoxins

SUNY Stony Brook/Portland State University · Chemistry · SUNY Stony Brook/Portland State University

Portland, OR

Phytochemicals with documented neurotoxicity and selective toxicology reviewed. Peripheral and central nervous system toxins covered and some somatic/autonomic medicines.

Jan 1987–
Aug 1992

  

Research: OTC Herbal Medicines benzylisoquinoline alkaloid content

Portland State University · Chemistry · Portland State University

Northwest natural products · Portland, OR

TLC biq content comparisons: Xanthoxylum american, X. clava-herculis, and X. bungeanum; Berberis nervosa, B. repens, B. officinalis, and Mahonia aquifolium; Phellodendron amurense; Magnolia officinalis; Eschscholtzia californica, Sanguinaria canadense, Hydrastis officinalis; Achlys triphylla, Vancouveria hexandra, Podophyllum peltatum, Caullophylum, Epidemium, Nandina sp.; Jatrorrhiza sp.; Fumaria spp., Menispermum lunatum; Papaver spp., Chelidonium majus, Argemone sp., Thalictrum spp.. Numerous isolation and identification tests performed for specific indicator alkaloids. TLCs performed using EtOH:dH2O (8:1, 9:1 and 9.5:1) and Ethyl acetate solvent systems, on silica-based, cellulose, and artificial paper-like cellulose-silica strips.

Jan 1987–May 1989  

Research: Frullanoside intoxication of local tree climbers and cutters

Portland State University · Chemistry · Portland State University

Chemistry Professor Al Levinson · Portland, OR

Unusual cases of type 1 immune reaction occur amongst workers who as part of their job requirements have to scale trees and cut their trunk in sections midway above the ground. These workers are typically exposed to bark, wood, lichen and liverwort dust as part of this work experience and are typically not advised of the dangers of exposure to dust particles produced by the local liverwort frullania. The toxicity and chemical make of frullania was investigated, revealing a series of sesquiterpene lactones (fruallnosides) were responsible for this immunotoxicity, induced through pulmonary intake of fine dust particulates onto bronchial and bronchiolar surfaces. Masks were recommended for protection against this type of exposure. Evidence of a genetic reason for this toxicity was non-conclusive, suggesting all tree scalers might be at risk.

Jan 1987–Aug 1991  

Research: Alkaloid, coumarin, neolignan, and tannin content of local Berberidaceae members

Portland State University · Chemistry · Portland State University

Portland, OR

Researched all local Berberidaceae members of Pacific Northwest Rainforests; focused on Achlys triphylla and Vancouveria hexandra using typical TLC/PC studies and chemical analysis techniques; documented chemical content of local rainforest herbaceous species with chemotaxonomic/phytoeconomic potential due to documented chemotherapeutic prospects for these compounds. Demonstrated differences in alkaloid content for 3 most popular wildcrafted herbal medicine species of berberis/mahonia. Compared alkaloid content of local species with European species and with two specimens obtained from the east coast of the US.

Jan 1986–Sep 2000  

Research: Modified or Adulterated Herbal Medicine Products

Portland State University · Chemistry · Portland State University

Northwest Natural Products · Portland, OR

Reports regarding herbal medicine and OTC nutritional related problems were regularly reported, followed by necessary documentation, company records and laboratory-based chemical reseaarch. More than 100 over-the-counter herbal medicines were monitored, and tested for unusual chemical and plant source make-up. The use of counterfeits, adulterants, and substitute ingredients was not unusual to this market, involving products of local, national and foreign origin. Most important projects (expected product<>alternative product): Uva ursi<>Buxus (alkaloidal); Scutellaria spp.<>Tecoma aspira (germander, hepatotoxic); Matricaria<>Chamaemelum (Chamomile substitute); Tussilago<>Petasites (hepatotoxic); non-toxic Aristolochia sp.<>toxic Aristolochia sp. (Chinese medicine); Symphytum (external use only)<>Symphytum (internal use product, hepatotoxic); Celandine Poppy<>Solanum sp. (imported India product with synonymous name); Tabebuia (pao d’arco)<>other T. species; Valeriana<> Middle East Ferula sumbula product; tryptophan<>TRP product contaminated with undetectable bioengineered tryptophan bis-related byproduct.

Jan 1986–Jun 1987  

Research: Investigation of a case of product contamination by heavy metals

Portland State University · Chemistry · Portland State University

Portland, OR

A dolomite over-the-counter remedy taken for its Calcium content was tested for possible heavy metal contamination due to its original natural mineral source. This dolomite mineral source was found to be contaminated by several metals, including palladium zinc and copper. This study took place as part of national program designed to uncover OTC product contamination, substitution, and counterfeiting practices. This dolomite product and other dolomite products were subsequently removed from the marketplace due to similar outcomes documented nationwide by numerous research groups.

Sep 1983–May 1984  

Research: OTC Products Design

JSP, Inc. · Nutritional Supplements

United States

Pharmaceutical

Jan 1983–Sep 1995  

Research: Revolutionary War Physician Dr. Cornelius Osborn’s Vade Mecum

SUNY at Stony Brook/Portland State University · Medicine/Chemistry · SUNY at Stony Brook/Portland State University

History of Medicine Research Group · Poughkeepsie, New York

Transcription, interpretation and analysis of a 1759 colonial New York physician’s manuscript (82 pp, 250 medicines). Includes reviews of physician’s/revolutionary war surgeon’s genealogy and biography, NY regional, demographic and medical histories; related pre and post-revolutionary War histories. Final work includes 500 pp materia medica review, vade mecum transcript with photos and footnotes, a discussion of medical, surgical and pharmacal philosophies for the time, a review and history of the related materia medica, and a review of 17th to 18th C philosophies and scientific reasons attached to each recipe and disease/pathology state made by physician. Unique special topics included in study: documentation of first example of Dutch-Jewish colonial medical practice by Ashkenazi physician Isaac Marks, 1720-50; documented example of Iroquois herbal medicine remedy, 1759; documented example of Robert Boyle-Boerrhaavian neo-alchemical lunarian or iron-based formulation for Ens Veneris (“essence of Venus”), a popular remedy for dysmenorrhea and delayed or lack of menses, 1759.

Jan 1983–Sep 2000

  

Research: History of Plant Use in Medicine

SUNY at Stony Brook/Portland State University · Chemistry · SUNY at Stony Brook/Portland State University

Stony Brook, NY/Portland, OR

The philosophy of regular and alternative medical practices developed in the New World and United States, ca. 1600 to 1865. A review and cataloguing of materia medica publications, family/domestic medical practice literature, professional documents and textbooks, regular and alternative schooling and practice histories. Changes in the history of the professions linked to major scientific discoveries and their “alternative interpretations”, and the evolution and changes in epidemic/endemic disease patterns and mortality rates.

Sep 1982–Apr 1990

  

Research: Toxidrome

SUNY at Stony Brook/Portland State University · School of Medicine/Chemistry · SUNY at Stony Brook/Portland State University

Stony Brook, NY/Portland, OR

Investigated, characterized, reclassified toxicity of more than 500 known domestic and wild plants based on NCMC-Howard Mofenson toxic syndrome classification techniques created ca. 1978. Developed database on toxins; tested database for use in identification of syndromes based on symptomatology/clinical signs; tested database for use in producing lists of potential causative agents based on symtpmatology. Examples of toxidromes: digitalis glycosides; steroidal alkaloids; tropanes; oxalates; pyrrolizidine hepatotoxins; furocoumarin-induced photosensitization; physostigmine/eserine; naphthaphenanthradenes.

Jan 1981–May 1981

  

Research: A mechanism for the formation of Long Island Iron Concretions (Indian Paint Pots)

Stony Brook University · Earth and Space Sciences · SUNY Stony Brook

MOLINS · Stony Brook, NY

The formation of Iron Concretions (Indian Paint Pots) on Long Island is due to a combination of historical landform events in combination with local climatic and meteorologic history and local vegetation history. The Indian Paint Pots of Long Island are unique in that many have a center or nucleus that is rich in very fine iron oxide powder. This powder is typically yellow to deep red in color, and has the ability to pass through all standard soil screens (min. 120 to 200 mesh). Reduced concretions typically lack this Fe-II and Fe-III oxidized powder, typically have a coarse and sandy internal surface, and at time contain well-preserved fossilized materials such as cross sections of plant branches or 1cm long twigs, each measuring 0.2 to 3 cm in diameters. Due to these findings, it has been theorized that iron dissolution and passage into deeper strata, followed by exposure to organic material, might result in aggregation of iron-rich materials to the surface and areas around negatively charged organic debris. As iron-based materials, either solubilized or non-solubilized, pass through the various substrata of sand layers, chemical change progresses and larger materials are filtered out. This enables the smallest particulates to aggregate in specifically-defined chemical/electrophilic areas. Following accumulation of thes position iron-based particulates and/or crystallized solutes, subsequent oxidation-reduction actions can then take place in the fairly porous sandy soils surrounding this material. In this way, well-defined oxidation and reduction layers form around the nucleus of the concretion area, leading to collection of the oxidized iron powders and nearby fusion of sand particles. These events require several thousand years to take place and innumerable percolation events, resulting in sand-rich layers underlying Long Island soil layers where the necessary redox reactions required for these events to take place occur. The most active redox layers tend occur at least one meter below the C-zone subsoil layer, and may be even deeper given the right combination of percolation-aeration events. These prime events are directly linked to the formation of Long Island as a gravel and sand-based moraine formation, well-documented as the result of two distinct glacial events.

Sep 1980–Jun 1982

  

Research: Use of a Birth Control/STD Student Health Services Clinic

Stony Brook University · Psychology · SUNY Stony Brook

EROS · Stony Brook, NY

Utilization of the on-campus birth control counseling/STD testing Gynecology/Birth Control clinic was monitored and statistically reported on a monthly, quarterly and annual basis. Results indicated peaks in utilization occur approximately 5 to 6 weeks into each semester, with pregnancy rates not impacted by counseling or peer-based educational services. Gynecological visit patterns remained active for pill use, education and prescription-filling visits, followed by increases in pregnancy testing, and abortion counseling visits. Pregnancy rates remained stable at about 15-25 pregnancies per semester (1-2 per week average, 6-8 per week peak), with gynecology/counseling visit rates ranging from 75-100 per week, for a population of approximately 30K (male and female) undergraduate and graduate students.

Jan 1980–Jul 1982

  

Research: Epilepsy, Seizures, and Cerebral Dominance

Stony Brook University · Psychology · SUNY Stony Brook

Left Brain, Right Brain · Stony Brook, NY

A study and review of documented seizure behaviors in relation to location of seizure focus, triggering events, emotional status, and documented electrical activities. The ICD classification method for seizure descriptions was reviewed. The potential value of well-documented, observed and otherwise well-reported seizure-related events was reviewed. A sequence of seizure-related activities was developed; reasons for cognitive/memory-changes proposed based on midbrain/reticular formation/pituitary activities; reasons for initial and subsequent (later) triggers based on sensory and emotional stimuli reviewed. The developmental process for a recurring seizure syndrome linked to possible establishment of intermediate (post-short term, days) and longterm (days-weeks+) memory features responsible for reassociating seizure related events to other recurring non-biological (limbic-emotional) stimuli not responsible for initial events.

Sep 1978–Aug 1984

  

Research: Long Island Plant Ecology

Stony Brook University · Earth and Space Sciences · SUNY Stony Brook

Museum of Long Island Natural Sciences, Herbarium · Stony Brook

Pine Barrens Ecology Endangered Species Protection Wetland Ecology

Jan 1977–May 1978

  

Research: Squid Axon Na+-K+ Channel Physiology

Stony Brook University · Biology · SUNY at Stony Brook

Stony Brook, NY

Squid Axon Na+-K+ exchange channel and end-receptor physiology were reviewed in relation to application of a variety of neurotoxins, including triethanolamine (TEA), tetrodotoxin (TTX), crude conotoxin (conus toxin or CTX), ouabain, strophanthidin G, and relatives. Reports included application of Michaelis-Menton equation.

Jan 1977–May 1977

  

Research: Impacts of Landuse Patterns on Wappinger Falls Lake Ecology

Stony Brook University · Environmental Engineering · SUNY Stony Brook

Stony Brook, NY

Impacts of the following on local riparian-lake ecology: species types and diversity, crop types and agricultural runoff patterns, population history, chemical release history by local 19th C factories, current factory/industry history and location, current soil type and distribution along a 15 mile tributary, topography and water runoff patterns.

Education  

  

Denver Health

The Implementation and Use of Quality Improvement Activity Reports for Monitoring Employee Population Health Statistics at Denver Health

United States · Denver, CO

Jan 2005

  

Denver Health

Tiermed Systems, LLC. TIERMED Systems/Compass Navigator training (NCQA-certified HEDIS software)

United States · Denver, CO

Jan 2005

  

Denver Health

NCQA: 2005 HEDIS, Data Management training, Update and Recertification

United States · Denver, CO

Jan 2005

  

Denver Health

NCQA/State Medicaid Program, State of Colorado Study: Engagement in Appropriate Preventive Care Program Activities by Prenatal/Postpartum Women

United States · Denver, CO

Jan 2005

  

Denver Health

NCQA: Medicare Choice and Medicaid Choice populations “Diabetes Care and Prevention”, Performance Improvement Projects, Data Management

United States · Denver, CO

Jan 2005

  

Denver Health

Denver Health, Employee Population Health Monitoring–utilizing intranet data

United States · Denver, CO

Jan 2004

  

Denver Health/Denver Health Managed Care

Denver Health MSIS/Integrated IS Training

United States · Denver, CO

Jan 2004

  

Denver Health

NCPDP Pharmacy Database training: datasets development and use

United States · Denver, CO

Jan 2004

  

Denver Health

NCQA: “Childhood Immunizations and Well-Visits” Medicaid Performance Improvement Project

United States · Denver, CO

Jan 2004

  

Denver Health

NCQA: 2004 HEDIS, Data Management training. Update and Recertification

United States · Denver, CO

Jan 2003

  

Denver Health

Denver Health Population Data, PEROT Systems training

United States · Denver, CO

Jan 2003

  

Denver Health

Colorado State Immunization Program Database training (annual)

United States · Denver, CO

Jan 2003

  

Denver Health

Electronic Lifetime Medical Records (patient medical records) training

United States · Denver, CO

Jan 2003

  

Denver Health

NCQA: 2003 HEDIS, Data Management training, Update and Certification

United States · Denver, CO

Jan 2002

  

Portland State University

Qualitative Analysis

United States · Portland, OR

Sep 2000–Jun 2002

  

Portland State University

Community Health/Public Health · MPH

United States · Portland, OR

Sep 1997–Aug 2000

  

Portland State University

Biogeography/medical geography · MS

United States · Portland, OR

Jan 1987–Aug 2000

  

Portland State University

Phytochemistry · Post-baccalaureate

United States · Portland, OR

Jan 1984

  

SUNY Stony Brook, School of Medicine/Medical Anthropology

Distinction in Research (D/R) Program, History of Medicine

United States · Stony Brook, NY

Sep 1982–Dec 1986

  

School of Medicine

Internal Medicine, Epidemiology, Pharmacology, History

United States · Stony Brook, NY

Sep 1976–Jun 1982

  

Stony Brook University

Biology · BS

United States · Stony Brook, NY

Sep 1976–Jun 1982

  

Stony Brook University

Earth and Space Sciences · BS

United States · Stony Brook, NY

Awards & achievements  

Jan 2007.  Award: Communications Award, ESRI, Health/GIS Conference (Received for developing an effective way to map West Nile ecology in relation to West Nile cases–predictive modeling of positive testing vectors and hosts)

 

Other Interests

 

Camping, hiking, some fishing.
Fossil hunting/rockhounding.

Annals of the American Association of Geographers
American Journal of Public Health
Environmental Health Journal
Bulletin of the History of Medicine
Economic Botany
Mankind Quarterly, AG Voronov. (Russian.) [Biogeography, medical geography and the theory of natural foci of human diseases.] Med Parazitol (Mosk). 1984 Mar-Apr;(2):28-33.

Alexander K. Johnston. The geographical distribution of health & disease, in connection chiefly with natural phenomena. (with) Fever districts of United States & W. Indies, on an enlarged scale. By A. Keith Johnston, F.R.S.E. &c. Engraved by W. & A.K. Johnston, Edinburgh. William Blackwood & Sons, Edinburgh & London. (1856). See: http://www.davidrumsey.com/maps940061-24722.html, and EW Gilbert. Pioneer Maps of Health and Disease in England. The Geographical Journal, Vol. 124, No. 2 (Jun., 1958), pp. 172-183. , Adrien Albert (past professor). Selective Toxicity. 1ed. 1953 to present.

Gurcharan Singh. Plant Systematics: an Integrated Approach. Science Publishers, 2004. (561 pp)